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Table 4 Association between the baseline white blood cell count and respiratory disease mortality in the Guangzhou Biobank Cohort Study, 2003–2016, excluding deaths within 2 years

From: White blood cell count and all-cause and cause-specific mortality in the Guangzhou biobank cohort study

Decile of WBC count, ×109/L (range) Multivariable modela (n = 29,672) Multivariable model in non-smokers a (n = 23,958)
HR (95% CI) P value HR (95% CI) P value
1st decile (f < 4. 5; m < 4.7) 1.28 (0.68, 2.41) 0.44 1.20 (0.52, 2.80) 0.67
2nd decile (f 4.5–4.8; m 4.7–5.2) 1.21 (0.65, 2.25) 0.56 1.07 (0.45, 2.54) 0.88
3rd decile (f 4.9–5.3; m 5.3–5.7) Reference   Reference  
4th decile (f 5.4–5.6; m 5.8–6.0) 1.50 (0.83, 2.72) 0.18 1.51 (0.69, 3.31) 0.31
5th decile (f 5.7–6.0; m 6.1–.4) 1.39 (0.78, 2.51) 0.27 1.45 (0.67, 3.14) 0.35
6th decile (f 6.1–6.3; m 6.5–6.8) 1.49 (0.81, 2.73) 0.20 1.74 (0.79, 3.85) 0.17
7th decile (f 6.4–6.8; m 6.9–7.2) 1.36 (0.75, 2.46) 0.31 1.39 (0.64, 3.03) 0.40
8th decile (f 6.9–7.3; m 7.3–7.8) 1.89 (1.08, 3.31) 0.03 1.91 (0.90, 4.04) 0.09
9th decile (f 7.4–8.2; m 7.9–8.7) 1.99 (1.13, 3.48) 0.02 2.13 (1.01, 4.48) 0.05
10th decile (f > 8.2; m > 8.8) 1.90 (1.08, 3.33) 0.03 1.79 (0.83, 3.84) 0.14
  1. a: adjusted for age, sex, education, occupation, smoking status, alcohol use, physical activity, self-rated health, body mass index, diabetes, triglycerides, high-density lipoprotein cholesterol, platelet count, haemoglobin, force vital capacity (FVC), forced expiratory volume in 1 s (FEV1), and self-reported respiratory disease (COPD, chronic bronchitis, emphysema, asthma, tuberculosis, pneumonia)