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Table 2 Demographic characteristics of the PROFILES Cohort

From: Examining relationships between age at diagnosis and health-related quality of life outcomes in prostate cancer survivors

Variable of Interest All patients N = 617 Age Category at Diagnosis p-value
< 61 years N = 106 61–70 years N = 307 71+ years N = 204
Body Mass Index [1st, 3rd quartiles] 26.3 [24.2, 28.3] 26.8 [24.8, 28.4] 26.2 [24.3, 28.4] 25.8 [23.9, 27.7] 0.032
Marital Status Not married 97 (15.8) 12 (11.3) 39 (12.8) 46 (22.8) 0.004
Married/Co-habiting 516 (84.2) 94 (88.7) 266 (87.2) 156 (77.2)
Education Lower 85 (14.0) 4 (3.8) 36 (11.8) 45 (22.5) <0.001
Secondary 366 (60.1) 70 (66.7) 176 (57.9) 120 (60.0)
University, higher 158 (25.9) 31 (29.5) 92 (30.3) 35 (17.5)
Smoking Status Never 140 (22.8) 34 (32.4) 64 (20.9) 42 (20.9) <0.001
Former 399 (65.1) 48 (45.7) 209 (68.1) 142 (70.7)
Current 74 (12.1) 23 (21.9) 34 (11.1) 17 (8.5)
Currently Employed No 512 (85.8) 56 (52.8) 274 (90.7) 182 (96.3) <0.001
Yes 85 (14.2) 50 (47.2) 28 (9.3) 7 (3.7)
SES (%) Low 98 (16.7) 15 (14.7) 35 (12.0) 48 (24.7) 0.002
Medium 238 (40.5) 39 (38.2) 120 (41.1) 79 (40.7)
High 252 (42.9) 48 (47.1) 137 (46.9) 67 (34.5)
Gleason Score (%) 2–6 329 (55.0) 63 (61.8) 178 (60.1) 88 (44.0) 0.003
7 175 (29.3) 29 (28.4) 75 (25.3) 71 (35.5)
8–10 94 (15.7) 10 (9.8) 43 (14.5) 41 (20.5)
Stage of Cancer (%) I 292 (47.9) 57 (54.8) 154 (50.3) 81 (40.5) 0.121
II 208 (34.1) 34 (32.7) 102 (33.3) 72 (36.0)
III 97 (15.9) 11 (10.6) 45 (14.7) 41 (20.5)
IV 13 (2.1) 2 (1.9) 5 (1.6) 6 (3.0)
Time since Diagnosis (years, %) < 2 10 (1.8) 1 (1.0) 5 (1.7) 4 (2.2) <0.001
2–4 280 (49.0) 35 (36.1) 143 (49.7) 102 (54.8)
4–6 272 (47.6) 54 (55.7) 139 (48.3) 79 (42.5)
> 6 9 (1.6) 7 (7.2) 1 (0.4) 1 (0.5)
Comorbidities (%) Heart Condition 124 (22.5) 15 (14.7) 56 (20.4) 53 (30.3) 0.006
Stroke 13 (2.5) 0 (0.0) 9 (3.4) 4 (2.6) 0.174
Hypertension 207 (37.6) 35 (34.7) 106 (37.9) 66 (38.8) 0.783
Asthma, Bronchitis, COPD 71 (13.2) 7 (7.0) 40 (14.6) 24 (14.6) 0.128
Diabetes 85 (15.7) 11 (10.9) 38 (14.0) 36 (21.3) 0.041
Ulcer 10 (1.9) 1 (1.0) 5 (1.9) 4 (2.5) 0.681
Kidney Disease 16 (3.0) 2 (2.0) 4 (1.5) 10 (6.1) 0.021
Liver Disease 2 (0.4) 0 (0.0) 2 (0.8) 0 (0.0) 0.693
Anemia/Blood Condition 25 (4.7) 2 (2.0) 10 (3.8) 13 (8.2) 0.040
Thyroid Disease 14 (2.6) 2 (2.0) 4 (1.5) 8 (4.9) 0.092
Depression 42 (8.0) 12 (11.9) 20 (7.5) 10 (6.3) 0.251
Arthritis 141 (26.1) 20 (19.6) 69 (25.4) 52 (31.3) 0.098
Backache 150 (28.0) 29 (28.4) 77 (28.2) 44 (27.5) 0.983
Rheumatism 42 (8.1) 7 (7.1) 24 (9.1) 11 (6.9) 0.674
Treatment Type (%) Prostatectomy 224 (36.7) 63 (60.0) 123 (40.5) 38 (18.8) <0.001
Radiation 278 (45.5) 41 (39.1) 148 (48.7) 89 (44.1) 0.204
Hormone Therapy 126 (20.6) 15 (14.3) 54 (17.8) 57 (28.2) 0.004
Active Surveillance/Watchful Waiting 27 (4.4) 5 (4.8) 12 (4.0) 10 (5.0) 0.850
  1. The bolded p-values are significant (< 0.05)