Table 2 Comparison of responders and non-responders to trial invite
|  | All invited n=8902a | Responded to invitation n = 1489 | Did not respond to invitation n = 7413 | Response rate (%) | Unadjusted OR for response to mailout (95% CI) | Adjusted OR for response to mailout (95% CI) | Test for trend (p) |
|---|---|---|---|---|---|---|---|
Age at invitation (years) | 67.3 (5.7) | 68.1 (5.1) | 67.2 (5.8) |  | 1.14 (1.08, 1.21)b | 1.19 (1.12, 1.26)b | < 0.001 |
Age at invitation | |||||||
 40-59 yrs | 976 (11.0%) | 124 (8.4%) | 852 (11.6%) | 12.7 |  |  |  |
 60-64 yrs | 1462 (16.4%) | 200 (13.5%) | 1262 (17.0%) | 13.7 |  |  |  |
 65-69 yrs | 2989 (33.6%) | 536 (36.0%) | 2453 (33.1%) | 17.9 |  |  |  |
 70-75 yrs | 3475 (39.0%) | 629 (42.2%) | 2846 (38.4%) | 18.1 |  |  |  |
Sex | |||||||
 Female | 1847 (20.7%) | 291 (19.5%) | 1556 (21.0%) | 15.8 | 1.00 | 1.00 |  |
 Male | 7055 (79.3%) | 1198 (80.5%) | 5857 (79.0%) | 17.0 | 1.07 (0.93, 1.23) | 1.25 (1.08, 1.45) | 0.004 |
Ethnicity | < 0.001c | ||||||
 White | 6223 (69.9%) | 1128 (75.8%) | 5095 (68.7%) | 18.1 | 1.00 | 1.00 |  |
 Black African or Caribbean | 272 (3.1%) | 34 (2.3%) | 238 (3.2%) | 12.5 | 0.74 (0.50, 1.07) | 0.67 (0.45, 0.98) | 0.040 |
 South Asian | 578 (6.5%) | 98 (6.6%) | 480 (6.5%) | 17.0 | 0.90 (0.70, 1.14) | 1.08 (0.84, 1.38) | 0.542 |
 Other Asian | 240 (2.7%) | 31 (2.1%) | 209 (2.8%) | 12.9 | 0.69 (0.47, 1.03) | 0.69 (0.46, 1.02) | 0.066 |
 Other/Mixed | 147 (1.7%) | 16 (1.1%) | 131 (1.8%) | 10.9 | 0.62 (0.36, 1.05) | 0.61 (0.36, 1.04) | 0.072 |
 Missing | 1442 (16.2%) | 182 (12.2%) | 1260 (17.0%) | 12.6 | 0.58 (0.48, 0.69) | 0.55 (0.46, 0.66) | < 0.001 |
IMD 2010 quintile | < 0.001c | ||||||
 1 (least deprived) | 1407 (15.8%) | 293 (19.7%) | 1114 (15.0%) | 20.8 | 1.00 | 1.00 |  |
 2 | 1531 (17.2%) | 285 (19.1%) | 1246 (16.8%) | 18.6 | 0.86 (0.70, 1.04) | 0.87 (0.72, 1.07) | 0.190 |
 3 | 1616 (18.2%) | 315 (21.2%) | 1301 (17.6%) | 19.5 | 0.80 (0.65, 0.98) | 0.85 (0.69, 1.05) | 0.139 |
 4 | 2725 (30.6%) | 420 (28.2%) | 2305 (31.1%) | 15.4 | 0.64 (0.52, 0.79) | 0.70 (0.56, 0.87) | 0.001 |
 5 (most deprived) | 1604 (18.0%) | 171 (11.5%) | 1433 (19.3%) | 10.7 | 0.46 (0.23, 0.33) | 0.52 (0.40, 0.68) | < 0.001 |
 Unknown | 19 (0.2%) | 5 (0.3%) | 14 (0.2%) | 26.3 |  |  |  |
QRisk2 score (%) | 25.2 (5.0) | 24.6 (4.5) | 25.3 (5.1) |  | 0.86 (0.81, 0.92)d | 0.82 (0.77, 0.88)d | < 0.001 |
 20–24.9% | 5357 (60.2%) | 968 (65.0%) | 4389 (59.2%) | 18.1 |  |  |  |
 25–29.9% | 2245 (25.2%) | 347 (23.3%) | 1898 (25.6%) | 15.5 |  |  |  |
 > 30% | 1300 (14.6%) | 174 (11.7%) | 1126 (15.2%) | 13.4 |  |  |  |