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Table 5 Quality Assessment of Cohort and Cross-Sectional Studies a

From: Recommendations for the screening of paediatric latent tuberculosis infection in indigenous communities: a systematic review of screening strategies among high-risk groups in low-incidence countries

First Author Year Study Design Objective clear Study population clearly specified Participation rate of eligible persons at least 50% Subjects recruited from the same or similar populations Sample size justification, or power analysis b Exposure(s) of interest measured prior to outcome(s) Timeframe sufficient to expect to see an association between exposure and outcome, if it exists Levels/categories of exposure measured, where applicable c Exposure measures clearly defined Exposure(s) assessed more than once over time Outcome measures clearly defined Outcome assessors blinded to exposure status of participants Loss to follow-up after baseline 20% or less Key potential confounding variables measured and statistically adjusted for Total (out of 14)
Gounder 2003 RC 1 1 1 1 1 1 1 1 1 x 1 x 1 1 12
Minodier 2010 PC 1 1 1 1 x 1 1 1 1 x 1 x x x 9
Panchal 2014 RC 1 1 1 1 1 1 1 1 1 x 1 x 1 1 12
Pareek 2011 CS 1 1 1 1 1 1 1 1 1 x 1 x 1 x 11
Pareek 2011b PC 1 1 1 1 x 1 1 1 1 x 1 x 1 1 11
Trehan 2008 PC 1 1 1 1 1 1 1 1 1 x 1 x 1 1 12
Alvarez 2014 PC 1 1 x 1 x 1 1 1 1 x 1 x 1 1 10
Yuan 1995 PC 1 1 x 1 x 1 1 1 1 x 1 x 1 1 10
Taylor 2008 CS 1 1 1 1 1 1 1 1 1 x 1 x 1 x 11
  1. 1 = criterion met x = criterion not met or not reported CS = Cross-Sectional RC = Retrospective Cohort PC = Prospective Cohort
  2. aBased on the National Heart, Lung and Blood Institute’s Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies, [16]
  3. bWhere studies sampled an entire population of interest (e.g. data available on all eligible individuals through health system records), a point was awarded for sample size justification)
  4. cWhere exposure was the absence / presence (introduction / cessation) of a particular screening strategy, “levels” of exposure are not applicable, as this exposure is dichotomous. In this case, studies were not deducted points