Impact of social determinants on antiretroviral therapy access and outcomes entering the era of universal treatment for people living with HIV in Italy

Table 2 Median CD4 cell count at time of enrolment in the ICONA cohort and at time of ART initiation according to socio-demographic characteristics

	CD4 at enrollment			CD4 at time of ART initiation
	Median	IQR	p	Median	IQR	p
	n/mmc	n/mmc	p	n/mmc	n/mmc	p
Gender
Male	439	260–621	0.453	360	223–520	< 0.001
Female	448	263–635	0.453	325	205–479	< 0.001
Age (years)
< 30	511	364–696	< 0.001	390	273–563	< 0.001
30–40	440	269–622		358	225–514
40–50	377	188–554		323	173–483
> 50	283	108–500		273	105–422
Mode of HIV transmission
HS	385	191–580	< 0.001	310	171–460	< 0.001
PWID	482	305–685		342	222–530
MSM	471	310–643		390	267–550
Residency area
North	499	336–694	< 0.001	333	232–460	< 0.001
Centre	443	270–634		302	193–436
South	432	248–646		330	205–516
Education
Elementary school	384	179–606	< 0.001	288	156–430	< 0.001
Junior high school	437	232–624		320	197–481
High school	438	261–613		353	224–505
University	464	299–637		393	272–569
Employement
Unemployed	439	264–644	< 0.001	342	216–523	< 0.001
Full time worker	450	279–626		351	225–506
Self employed	437	249–621		351	222–510
Temporary employed	467	320–650		340	220–506
Student	540	385–700		443	325–648
Retired	326	131–534		274	121–440
Housewife	390	157–590		302	122–427
Year of ART initiation/last observation
2002–2006	465	278–661	< 0.001	292	185–448	< 0.001
2007–2011	385	232–554		305	196–409
2012–2016	460	270–637		414	262–574