Table 2 Overview of indicators, methods, and time points of data collection

Informed consent

X

Eligibility screen

Frailty state^d

Fried frailty criteria [19], medical questionnaire, additional screening questionnaire (optional)

X

Allocation

X

X

Outcomes

Indicators

Method

Socio-demographics

Age, gender, education, ethnic background, marital status, job status, smoking

Participant questionnaire [21]

X

X

Disease history

Participant questionnaire [21]

X

X

Height

Stadiometer

X

X

Nutritional status^d

SNAQ [20]

X

Olfactory function

Sniffin’ sticks [22]

X

X

Meal functionalities

Questionnaire [23]

X

X

Overall

Quality of life

EQ-5D-5L [25]^e

X

X

X

X

X

X

X

X

X

X

Long-term

Physical functioning / fitness

SPPB [27], TUG [28, 29], 6MWT [30]

X

X

X

X

X

X

X

X

X

X

Basic Lower Extremity function questionnaire [32]

X

X

X

X

X

X

X

Lower extremity strength

3-RM on leg press and leg extension

X

X

X

X

Knee extension with hand held dynamometer (MicroFET)

X

X

X

X

X

X

X

X

X

X

Body composition (lean mass, fat mass, hydration status) and weight

DXA, BIS

X

X

X

X

X

X

Weighing scale

X

X

X

X

X

X

X

X

X

X

Social participation

Social Role Domain questionnaire [36]

X

X

X

X

X

X

X

Intermediate

Dietary / protein intake

3-day food diaries

X

X

X

X

X

X

X

Urinary nitrogen^f

X

X

X

X

X

X

Physical activity

LAPAQ [37]

X

X

X

X

X

X

X

Actigraph^g

X

X

Initial

Behavioural determinants

Participant questionnaire (based on [38,39,40,41,42,43,44,45])

X

X

X

X

X

X