| |
Informed consent
|
X
| | | | | | | | | | |
Eligibility screen
|
Frailty stated
|
Fried frailty criteria [19], medical questionnaire, additional screening questionnaire (optional)
|
X
| | | | | | | | | | |
Allocation
| | | |
X
|
X
| | | | | | | | |
Outcomes
|
Indicators
|
Method
| | | | | | | | | | | |
Socio-demographics
|
Age, gender, education, ethnic background, marital status, job status, smoking
|
Participant questionnaire [21]
| |
X
|
X
| | | | | | | | |
Disease history
|
Participant questionnaire [21]
| |
X
|
X
| | | | | | | | |
Height
|
Stadiometer
| |
X
|
X
| | | | | | | | |
Nutritional statusd
|
SNAQ [20]
|
X
| | | | | | | | | | |
Olfactory function
|
Sniffin’ sticks [22]
| |
X
|
X
| | | | | | | | |
Meal functionalities
|
Questionnaire [23]
| |
X
|
X
| | | | | | | | |
Overall
|
Quality of life
|
EQ-5D-5L [25]e
| |
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
Long-term
|
Physical functioning / fitness
|
SPPB [27], TUG [28, 29], 6MWT [30]
| |
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
Basic Lower Extremity function questionnaire [32]
| |
X
|
X
|
X
|
X
|
X
|
X
| |
X
| | |
Lower extremity strength
|
3-RM on leg press and leg extension
| |
X
|
X
|
X
|
X
| | | | | | |
Knee extension with hand held dynamometer (MicroFET)
| |
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
Body composition (lean mass, fat mass, hydration status) and weight
|
DXA, BIS
| |
X
|
X
|
X
|
X
|
X
|
X
| | | | |
Weighing scale
| |
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
X
|
Social participation
|
Social Role Domain questionnaire [36]
| |
X
|
X
|
X
|
X
|
X
|
X
| |
X
| | |
Intermediate
|
Dietary / protein intake
|
3-day food diaries
| |
X
|
X
|
X
|
X
|
X
|
X
| |
X
| | |
Urinary nitrogenf
| |
X
|
X
|
X
|
X
|
X
|
X
| | | | |
Physical activity
|
LAPAQ [37]
| |
X
|
X
|
X
|
X
|
X
|
X
| |
X
| | |
Actigraphg
| |
X
|
X
| | | | | | | | |
Initial
|
Behavioural determinants
|
Participant questionnaire (based on [38,39,40,41,42,43,44,45])
| |
X
|
X
|
X
|
X
|
X
|
X
| | | | |