Table 1 Cognitive domains and tests performed within the CANTAB cognitive assessment battery

1

Processing speed including visual motor integration

Reaction Time (RTI)

Perception of visual stimuli, response to visual stimuli and execution of motor action

movement time, reaction time and response accuracy;

6 min

Motor Screening (MOT)

Sensorimotor or perceptual motor speed and comprehension difficulties

Time lapse between display to response; number of correct and incorrect responses

2 min

2

Memory including executive Functioning

Spatial Working Memory (SWM)-

Manipulation of visuo-spatial information, executive demands of strategy (reasoning, decision making and behaviour), parts of short-term memory (holding) concerned with immediate conscious perceptual and linguistic processing

Visits, re-visits and searches for boxes

5 min

Paired Associate Learning (PAL)

Visual memory and new learning, episodic memory (collection of past, personal experience that occurred at a particular time and place with associated emotions)

Incorrect selection, adjustment, problem solving and memory of selection

8 min

3

Attention

Attention Switching Task (AST)

Attentional set-shifting, cognitive flexibility and lateralization

Congruency and latency during change of instructions

8 min

Rapid Visual Information Processing (RVP)

Sustained attention and continuous performance, impulse control or inhibition

Sensitivity to target and correct responses

7 min