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Table 1 Univariable longitudinal analysis (using GEE) of characteristics of participating girls over time

From: Changes in (risk) behavior and HPV knowledge among Dutch girls eligible for HPV vaccination: an observational cohort study

  Round 1b Round 2 Round 3 Round 4 Round 5   
Category n (%) n (%) n (%) n (%) n (%) p-value OR (+ 95% CI)
Participants
 Unvaccinated 1051 (100) 679 (65) 565 (54) 572 (54) 502 (48)   
 Vaccinated 1938 (100) 1361 (70) 1213 (63) 1217 (63) 1072 (55)   
Median age (range)
 Unvaccinated 17 (16–17) 17 (17–18) 18 (18–19) 19 (18–19) 19 (19–20)   
 Vaccinated 17 (16–17) 17 (17–18) 18 (18–19) 19 (18–19) 19 (19–20)   
More urban areas (> 1000 inhabitants)
 Unvaccinated 495 (47) 315 (47) 278 (49) 308 (55) 282 (57) < 0.01 Ref
 Vaccinated 1019 (53) 714 (53) 712 (59) 734 (61) 685 (65) < 0.01 1.28 (1.10–1.47)
Low/Middle Educationa
 Unvaccinated 434 (42) 235 (35) 189 (34) 180 (32) 153 (31) 0.10 Ref
 Vaccinated 779 (40) 465 (35) 394 (33) 386 (32) 324 (30) 0.07 0.96 (0.83–1.11)
Ever have used alcohol
 Unvaccinated 751 (72) 507 (76) 431 (77) 449 (79) 389 (78) < 0.01 Ref
 Vaccinated 1509 (78) 1107 (82) 988 (82) 1021 (84) 888 (83) < 0.01 1.46 (1.24–1.70)
Ever smoked
 Unvaccinated 261 (25) 176 (26) 152 (27) 55 (10) 52 (10) < 0.01 Ref
 Vaccinated 443 (23) 330 (24) 296 (25) 125 (10) 107 (10) < 0.01 0.92 (0.79–1.09)
Ever used contraception
 Unvaccinated 640 (64) 443 (68) 395 (71) 420 (75) 359 (75) < 0.01 Ref
 Vaccinated 1380 (72) 1038 (78) 973 (81) 1020 (85) 889 (86) < 0.01 1.69 (1.45–1.97)
Ever had sex
 Unvaccinated 525 (52) 390 (60) 362 (65) 383 (70) 349 (71) < 0.01 Ref
 Vaccinated 1070 (56) 845 (64) 845 (71) 914 (76) 833 (80) < 0.01 (c1) 1.19 (1.02–1.39)
        (c2) 1.30 (1.24–1.35)
        (c3) 1.06 (1.00–1.12)
  1. The p-value indicates whether there is a significant change over time. The OR indicates possible differences between vaccinated and unvaccinated participants overall (across all five time points)
  2. aLow/Middle = no/primary education, lower general to intermediate vocational secondary education; High = higher vocational/general secondary education, (pre)university education
  3. bPreviously published by Mollers et al. [17]
  4. cSignificant interaction time and vaccination status; 1: OR for vaccination status at round one, 2: OR for round, 3: OR for interaction between vaccination status and round