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Table 1 Univariable longitudinal analysis (using GEE) of characteristics of participating girls over time

From: Changes in (risk) behavior and HPV knowledge among Dutch girls eligible for HPV vaccination: an observational cohort study

 

Round 1b

Round 2

Round 3

Round 4

Round 5

  

Category

n (%)

n (%)

n (%)

n (%)

n (%)

p-value

OR (+ 95% CI)

Participants

 Unvaccinated

1051 (100)

679 (65)

565 (54)

572 (54)

502 (48)

  

 Vaccinated

1938 (100)

1361 (70)

1213 (63)

1217 (63)

1072 (55)

  

Median age (range)

 Unvaccinated

17 (16–17)

17 (17–18)

18 (18–19)

19 (18–19)

19 (19–20)

  

 Vaccinated

17 (16–17)

17 (17–18)

18 (18–19)

19 (18–19)

19 (19–20)

  

More urban areas (> 1000 inhabitants)

 Unvaccinated

495 (47)

315 (47)

278 (49)

308 (55)

282 (57)

< 0.01

Ref

 Vaccinated

1019 (53)

714 (53)

712 (59)

734 (61)

685 (65)

< 0.01

1.28 (1.10–1.47)

Low/Middle Educationa

 Unvaccinated

434 (42)

235 (35)

189 (34)

180 (32)

153 (31)

0.10

Ref

 Vaccinated

779 (40)

465 (35)

394 (33)

386 (32)

324 (30)

0.07

0.96 (0.83–1.11)

Ever have used alcohol

 Unvaccinated

751 (72)

507 (76)

431 (77)

449 (79)

389 (78)

< 0.01

Ref

 Vaccinated

1509 (78)

1107 (82)

988 (82)

1021 (84)

888 (83)

< 0.01

1.46 (1.24–1.70)

Ever smoked

 Unvaccinated

261 (25)

176 (26)

152 (27)

55 (10)

52 (10)

< 0.01

Ref

 Vaccinated

443 (23)

330 (24)

296 (25)

125 (10)

107 (10)

< 0.01

0.92 (0.79–1.09)

Ever used contraception

 Unvaccinated

640 (64)

443 (68)

395 (71)

420 (75)

359 (75)

< 0.01

Ref

 Vaccinated

1380 (72)

1038 (78)

973 (81)

1020 (85)

889 (86)

< 0.01

1.69 (1.45–1.97)

Ever had sex

 Unvaccinated

525 (52)

390 (60)

362 (65)

383 (70)

349 (71)

< 0.01

Ref

 Vaccinated

1070 (56)

845 (64)

845 (71)

914 (76)

833 (80)

< 0.01

(c1) 1.19 (1.02–1.39)

       

(c2) 1.30 (1.24–1.35)

       

(c3) 1.06 (1.00–1.12)

  1. The p-value indicates whether there is a significant change over time. The OR indicates possible differences between vaccinated and unvaccinated participants overall (across all five time points)
  2. aLow/Middle = no/primary education, lower general to intermediate vocational secondary education; High = higher vocational/general secondary education, (pre)university education
  3. bPreviously published by Mollers et al. [17]
  4. cSignificant interaction time and vaccination status; 1: OR for vaccination status at round one, 2: OR for round, 3: OR for interaction between vaccination status and round