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Table 2 Hazard ratios (HR) and 95% confidence intervals for onset of long term sickness absence (LTSA) within follow up period across levels of depressive symptoms and number of pain locations

From: Comorbid symptoms of depression and musculoskeletal pain and risk of long term sickness absence

  Crude Model 1 Model 2 Model 3
  HR 95% CI HR 95% CI HR 95% CI HR 95% CI
Number of pain locations
 0 ref   ref   ref   ref  
 1 1.52 (1.26 to 1.82) 1.50 (1.24 to 1.80) 1.44 (1.18 to 1.77) 1.57 (1.26 to 1.95)
 2 1.79 (1.50 to 2.13) 1.73 (1.45 to 2.07) 1.56 (1.28 to 1.90) 1.65 (1.33 to 2.04)
 3 2.08 (1.72 to 2.53) 1.94 (1.58 to 2.37) 1.81 (1.45 to 2.27) 2.00 (1.56 to 2.57)
Depressive symptoms
 low ref   ref   ref   ref  
 medium 1.31 (1.33 to 1.59) 1.17 (0.98 to 1.40) 1.09 (0.89 to 1.33) 1.52 (0.86 to 2.70)
 high 1.60 (1.30 to 1.96) 1.36 (1.10 to 1.70) 1.35 (1.06 to 1.72) 3.07 (1.55 to 6.08)
Interaction terms
 1 pain & medium dep        0.52 (0.25 to 1.08)
 1 pain & high dep        0.50 (0.22 to 1.16)
 2 pain & medium dep        0.86 (0.45 to 1.64)
 2 pain & high dep        0.32 (0.14 to 0.71)
 3 pain & medium dep        0.61 (0.31 to 1.21)
 3 pain & high dep        0.43 (0.19 to 0.96)
Wald(p)/ df dep:62.7(0.00)/2 pain:27.(0.00)/3 74.(0.00)/5   70.81(0.00)/11   81.79(0.00)/17
  1. Model 1: Number of pain locations and depressive symptoms are included in the same model (mutually adjusted)
  2. Model 2: Number of pain locations and depressive symptoms are mutually adjusted and further adjusted for age, seniority and cohabitation