Skip to main content

Table 1 Summary of the study profile

From: Integrating use of point-of-care circulating cathodic antigen rapid diagnostic tests by community health workers during mass drug administration campaigns to improve uptake of praziquantel treatment among the adult population at Kome Island, North-Western Tanzania: a cluster randomized community trial

Study design Cluster randomized controlled community trial
Intervention Community health workers testing for Schistosoma mansoni infection using Point-of-care Circulating Cathodic Antigen test before offering treatment
Control Mass drug administration using praziquantel without testing for Schistosoma mansoni infection as per current practice
Primary outcome Proportion of study participants provided with praziquantel drug (treatment coverage) and geographical cluster (a service area of the community health workers) in the intervention and control arms
Cluster eligibility criteria Having more than 60 adult individuals served by two community health workers
Inclusion Individuals aged ≥18 years residing in a study cluster (s), willing to participate and give written informed consent
Exclusion Pregnant women at the time of treatment, history of adverse reaction to praziquantel and acutely ill at the time of treatment
Sampling eligibility criteria Residents of the selected clusters or residents of Kome island
Sampling exclusion criteria Non-resident of the cluster or Kome island as identified by community health workers participating in the study
Sample size per arm Total sample size (N = 4500), Intervention arm (n = 2250) and control (n = 2250)