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Table 6 Multiple comorbidities associated with global self-rated health stratified by age and educational level

From: Association between multiple comorbidities and self-rated health status in middle-aged and elderly Chinese: the China Kadoorie Biobank study

 

Age

P for interaction

Education level

P for interaction

30-59 yr

≥ 60 yr

No formal education

Primary school

Middle school or higher

OR

95% CI

OR

95% CI

OR

95% CI

OR

95% CI

OR

95% CI

Cardiometabolic diseases

 Coronary heart disease

3.03

2.84,3 .24

2.50

2.37, 2.64

< 0.001

2.42

2.18, 2.70

2.59

2.40, 2.80

2.56

2.42, 2.71

0.79

 Rheumatic heart disease

3.06

2.47, 3.78

3.68

2.62, 5.16

0.55

3.12

2.12, 4.58

3.57

2.52, 5.03

3.01

2.34, 3.87

0.71

 Stroke

3.33

3.04, 3.65

2.98

2.77, 3.21

< 0.001

3.08

2.68, 3.54

2.92

2.64, 3.23

2.94

2.72, 3.19

0.40

 Hypertension

1.27

1.25, 1.29

1.19

1.16, 1.22

< 0.001

1.14

1.11, 1.18

1.21

1.18, 1.23

1.32

1.29, 1.34

< 0.001

 Diabetes

1.83

1.76, 1.89

1.71

1.64, 1.79

< 0.001

1.70

1.61, 1.81

1.67

1.59, 1.75

1.88

1.81, 1.96

< 0.001

Respiratory diseases

 Tuberculosis

1.67

1.56, 1.79

1.35

1.25, 1.46

< 0.001

1.70

1.46, 1.98

1.45

1.32, 1.60

1.47

1.37, 1.57

0.10

 Emphysema/bronchitis

2.66

2.51, 2.81

2.27

2.13, 2.42

< 0.001

2.79

2.55, 3.04

2.77

2.57, 2.97

2.04

1.91, 2.18

< 0.001

 Asthma

2.16

1.93, 2.41

1.92

1.64, 2.25

0.04

1.86

1.51, 2.30

2.02

1.70, 2.42

2.14

1.89, 2.42

0.66

Musculoskeletal diseases

 Fracture

1.10

1.07, 1.13

1.09

1.05, 1.15

0.03

1.25

1.18, 1.31

1.10

1.05, 1.15

1.05

1.02, 1.09

0.06

 Rheumatoid arthritis

1.97

1.87, 2.09

1.58

1.47, 1.71

< 0.001

1.83

1.66, 2.02

1.77

1.63, 1.92

1.87

1.75, 2.00

0.58

Mental diseases

 Depressive Symptoms

2.58

2.34, 2.84

2.71

2.20, 3.34

0.93

2.83

2.34, 3.42

2.52

2.17, 2.92

2.67

2.35, 3.05

0.55

 Psychiatric disorders

2.28

2.02, 2.58

1.75

1.40, 2.19

0.002

2.34

1.90, 2.88

2.02

1.68, 2.44

2.24

1.90, 2.65

0.39

 Neurasthenia

2.42

2.24, 2.61

1.64

1.47, 1.83

< 0.001

2.39

2.07, 2.76

2.13

1.89, 2.41

2.06

1.90, 2.25

0.72

Digestive diseases

 Cirrhosis/chronic hepatitis

1.81

1.70, 1.93

1.40

1.24, 1.57

< 0.001

1.55

1.33, 1.80

1.67

1.51, 1.85

1.72

1.60, 1.86

0.69

 Peptic ulcer

1.82

1.76, 1.89

1.40

1.32, 1.49

< 0.001

1.81

1.67, 1.96

1.74

1.64, 1.85

1.63

1.56, 1.70

0.04

 Gallstone/gallbladder disease

1.69

1.64, 1.74

1.40

1.33, 1.47

< 0.001

1.64

1.56, 1.73

1.63

1.56, 1.71

1.54

1.48, 1.59

0.12

Cancer

2.79

2.46, 3.17

2.41

2.08, 2.81

0.004

2.70

2.15, 3.40

2.45

2.07, 2.89

2.62

2.28, 3.01

0.73

Other diseases

 Kidney disease

1.70

1.61, 1.81

1.48

1.33, 1.64

< 0.001

1.83

1.58, 2.13

1.68

1.52, 1.85

1.57

1.47, 1.68

0.16

 Head injury

1.21

1.13, 1.29

1.04

0.92, 1.18

0.001

1.26

1.07, 1.48

1.24

1.12, 1.37

1.15

1.07, 1.24

0.49

  1. Abbreviations: CI confidence intervals, OR odds ratio
  2. Odds ratios (95% CI) were calculated after adjustment of age, sex, study location, marital status, household income, education level, occupation, alcohol drinking, cigarette smoking, physical activity, BMI, family history of five diseases (stroke, heart attack, diabetes, mental disorders and cancer) and all comorbidities, except for the stratified variable in the corresponding stratified analysis