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Table 2 Associations between anthropometric indices and incident type 2 diabetes, Tehran Lipid and Glucose Study (1999–2015)

From: Optimal cut-points of different anthropometric indices and their joint effect in prediction of type 2 diabetes: results of a cohort study

 

Univariate model

Model 1b

Model 2c

HRa (95% CI)

P-value

HR (95% CI)

P-value

HR (95% CI)

P-value

Men

 BMI (kg/m2)

1.69 (1.54–1.85)

< 0.001

1.37 (1.24–1.51)

< 0.001

1.48 (1.31–1.68)

< 0.001

 WC (cm)

1.69 (1.52–1.87)

< 0.001

1.35 (1.21–1.50)

< 0.001

1.43 (1.26–1.64)

< 0.001

 WHtR

1.66 (1.51–1.83)

< 0.001

1.36 (1.23–1.50)

< 0.001

1.39 (1.24–1.55)

< 0.001

 WHR

1.52 (1.38–1.67)

< 0.001

1.27 (1.14–1.41)

< 0.001

1.26 (1.13–1.40)

< 0.001

 HC (cm)

1.52 (1.38–1.67)

< 0.001

1.25(1.14–1.37)

< 0.001

0.92(0.80–1.06)

0.304

Women

 BMI (kg/m2)

1.74 (1.60–1.89)

< 0.001

1.42 (1.30–1.56)

< 0.001

1.41 (1.27–1.57)

< 0.001

 WC (cm)

1.90 (1.74–2.08)

< 0.001

1.48 (1.34–1.64)

< 0.001

1.46 (1.30–1.64)

< 0.001

 WHtR

1.93 (1.76–2.12)

< 0.001

1.51 (1.37–1.68)

< 0.001

1.47 (1.32–1.64)

< 0.001

 WHR

1.57 (1.44–1.71)

< 0.001

1.30 (1.19–1.42)

< 0.001

1.27 (1.16–1.39)

< 0.001

 HC (cm)

1.46 (1.35–1.58)

< 0.001

1.24(1.14–1.35)

< 0.001

1.11(1.00–1.24)

0.043

  1. aPer 1 SD increase for each index (SD of WC = 11.13, BMI = 4.08, HC = 7.16, WHR = 0.06, WHtR = 0.06 in men and WC = 12.31, BMI = 4.90, HC = 9.51, WHR = 0.07, WHtR = 0.08 in women)
  2. bAdjusted for age (in time-scale manner), education level, family history of type 2 diabetes, systolic blood pressure, fasting plasma glucose, and triglyceride to high-density lipoprotein cholesterol ratio
  3. cAdjusted for model 1 variables and wrist circumference
  4. HR hazard ratio, CI confidence interval, BMI body mass index, WC waist circumference, WHtR waist to height ratio, WHR waist to hip ratio, HC hip circumference