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Table 2 Frequency distribution of patient characteristic variables for people initiating daily-dose isoniazid treatment and the proportion of people completing treatment by each characteristic. Treatment completion was categorized as 1) less than 6 months completed, 2) at least 6 months but less than 9 months completed, and 3) 9 or more months completed

From: Predictors of latent tuberculosis infection treatment completion in the US private sector: an analysis of administrative claims data

  

Distribution

% Achieving Each Level of Isoniazid Treatment Completion

% Completing ≥6 Mo.

N

% or Mean of Total

< 6 Months Complete

[% or Mean]

≥6 but < 9 Months Complete

[% or Mean]

≥9 Months Complete

[% or Mean]

p-value: 3 Completion Levels

≥6 Months Complete

[% or Mean]

p-value: < 6 vs ≥6 Months Complete

Sex

Female

575

53.6%

55.8%

22.1%

22.1%

0.232

44.2%

0.158

Male

497

46.4%

51.5%

25.4%

23.1%

 

48.5%

 

Age Group

0–14

105

9.8%

43.8%

24.8%

31.4%

0.019

56.2%

0.064

15–29

291

27.1%

58.8%

23.4%

17.9%

 

41.2%

 

30–44

321

29.9%

53.9%

25.2%

20.9%

 

46.1%

 

45–64

355

33.1%

52.7%

22.0%

25.3%

 

47.3%

 

Census Region

Northeast

352

32.8%

54.8%

20.5%

24.7%

0.148

45.2%

0.151

Midwest

174

16.2%

52.3%

25.3%

22.4%

 

47.7%

 

South

148

13.8%

61.5%

22.3%

16.2%

 

38.5%

 

West

398

37.1%

53.8%

23.6%

22.6%

 

46.2%

 

Patient Location

Large central metro county

484

45.1%

50.0%

26.7%

23.4%

0.169

50.0%

0.066

Large fringe metro county

413

38.5%

57.6%

19.6%

22.8%

 

42.4%

 

Any smaller county

175

16.3%

55.4%

24.6%

20.0%

 

44.6%

 

% of Households Under FPL in County

< 15%

596

55.6%

51.7%

22.8%

25.5%

0.035

48.3%

0.115

≥15%

476

44.4%

56.5%

24.6%

18.9%

 

43.5%

 

Insurance Type

HMO

188

17.5%

62.2%

21.3%

16.5%

0.005

37.8%

0.022

POS

742

69.2%

52.8%

25.1%

22.1%

 

47.2%

 

PPO

142

13.2%

47.9%

19.0%

33.1%

 

52.1%

 

INH Days Supply Received on Date of 1st Fill

< 2 month supply

991

92.4%

54.5%

24.1%

21.4%

0.020

45.5%

0.126

≥2 month supply

81

7.6%

45.7%

17.3%

37.0%

 

54.3%

 

Year INH Regimen Started

2011 Q3–4

230

21.5%

58.3%

23.0%

18.7%

0.308

41.7%

0.298

2012 Q1–4

450

42.0%

54.4%

21.8%

23.8%

 

45.6%

 

2013 Q1–4

346

32.3%

50.3%

26.3%

23.4%

 

49.7%

 

2014 Q1

46

4.3%

52.2%

23.9%

23.9%

 

47.8%

 

State TB Rate

–

 

3.85

3.84

3.81

0.846

3.83

0.864

LTBI Diagnostic Test

TST

441

41.1%

53.5%

22.9%

23.6%

< 0.001

46.5%

0.005

IGRA

219

20.4%

45.2%

23.7%

31.1%

 

54.8%

 

Unknown/ Other

412

38.4%

58.7%

24.3%

17.0%

 

41.3%

 

Percent Foreign Born in County

–

 

19.96

20.24

20.97

0.403

20.60

0.516

Count of Clinical Risk Factors

None

662

61.8%

58.0%

22.2%

19.8%

0.011

42.0%

0.002

1

304

28.4%

47.7%

27.0%

25.3%

 

52.3%

 

2 or more

106

9.9%

45.3%

22.6%

32.1%

 

54.7%

 

Diagnosis of Contact w/ TBa

No diagnosis

923

86.1%

54.3%

23.8%

21.9%

0.296

45.7%

0.457

Had diagnosis

149

13.9%

51.0%

22.2%

26.9%

 

49.0%

 

History of TB/ Late Effects

No diagnosis

1027

95.8%

54.2%

23.1%

22.7%

0.426

45.8%

0.197

Had diagnosis

45

4.2%

44.4%

35.6%

20.0%

 

55.6%

 

HIV Positive

No diagnosis

1030

96.1%

54.7%

23.4%

21.9%

0.004

45.3%

0.007

Had diagnosis

42

3.9%

33.3%

28.6%

38.1%

 

66.7%

 

Diabetes

No diagnosis

999

93.2%

54.5%

23.5%

22.0%

0.085

45.6%

0.126

Had diagnosis

73

6.8%

45.2%

24.7%

30.1%

 

54.8%

 

Tobacco

No diagnosis or medication

1004

93.7%

54.2%

23.7%

22.1%

0.237

45.8%

0.366

Had diagnosis or medication

68

6.3%

48.5%

22.1%

29.4%

 

51.5%

 

Immuno-suppressive Medication

No medication

948

88.4%

55.1%

23.0%

21.9%

0.030

44.9%

0.025

Had medication

124

11.6%

44.4%

28.2%

27.4%

 

55.6%

 
  1. aBased on an ICD-9-CM code of V01.1. Abbreviations: INH isoniazid, FPL federal poverty level, TB tuberculosis, TST tuberculin skin test, IGRA interferon-gamma release assays, LTBI latent tuberculosis infection, HMO health maintenance organization, POS point of service, PPO preferred provider organization