|
Hypothetical risk ratio
|
Specificity (%)
|
Incidence peripheral neuropathy
|
True GBS risk ratio a
|
Expected observed risk ratio b
|
PFP c (%)
|
Number of false positive GBS cases
|
|---|
|
1
|
100.0
|
3.3/10,000
|
1.00
|
1.00
|
0.0
|
0
|
|
1
|
91.7
| | | |
54.5
|
454
|
|
1
|
88.9
| | | |
62.4
|
631
|
|
1
|
80.6
| | | |
75.2
|
1153
|
|
5
|
100.0
|
3.3/10,000
|
1.29
|
1.29
|
0.0
|
0
|
|
5
|
91.7
| | |
1.18
|
40.7
|
414
|
|
5
|
88.9
| | |
1.16
|
49.4
|
591
|
|
5
|
80.6
| | |
1.12
|
64.8
|
1113
|
|
10
|
100.0
|
3.3/10,000
|
1.47
|
1.47
|
0.0
|
0
|
|
10
|
91.7
| | |
1.33
|
29.2
|
364
|
|
10
|
88.9
| | |
1.30
|
37.9
|
540
|
|
10
|
80.6
| | |
1.23
|
54.6
|
1063
|
|
1
|
100.0
|
5.6/10,000
|
1.00
|
1.00
|
0.0
|
0
|
|
1
|
91.7
| | | |
68.4
|
822
|
|
1
|
88.9
| | | |
74.7
|
1122
|
|
1
|
80.6
| | | |
84.1
|
2012
|
|
5
|
100.0
|
5.6/10,000
|
1.29
|
1.29
|
0.0
|
0
|
|
5
|
91.7
| | |
1.14
|
56.4
|
782
|
|
5
|
88.9
| | |
1.12
|
64.2
|
1082
|
|
5
|
80.6
| | |
1.08
|
76.5
|
1971
|
|
10
|
100.0
|
5.6/10,000
|
1.47
|
1.47
|
0.0
|
0
|
|
10
|
91.7
| | |
1.27
|
45.3
|
731
|
|
10
|
88.9
| | |
1.24
|
53.8
|
1032
|
|
10
|
80.6
| | |
1.17
|
68.5
|
1921
|
- a Risk ratio of GBS during the ZIKV outbreak, assuming sensitivity of 82.1% and specificity of 100% for the diagnosis of GBS; b Risk ratio of GBS during the ZIKV outbreak, after accounting for misclassification of GBS; c Proportion of false positive cases of GBS
