From: Drug prescribing during pregnancy in a central region of Italy, 2008-2012
Inappropriate drug prescriptionsa | Teratogen drug prescriptions | Progestogen drug prescriptions | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
% | OR adj | IC 95% (inf-sup) | % | OR adj | IC 95% (inf-sup) | % | OR adj | IC 95% (inf-sup) | |||
Socio-demographic variables | |||||||||||
Age classes | ≤34 | 5.4 | 1 | 0.7 | 1 | 15.8 | 1 | ||||
35-39 | 7.8 | 1.54 | 1.47-1.61 | 0.9 | 1.45 | 1.29-1.64 | 25.4 | 1.88 | 1.83 | 1.92 | |
≥40 | 11.4 | 2.23 | 2.08-2.38 | 1.2 | 1.99 | 1.68-2.35 | 33.5 | 2.68 | 2.58 | 2.79 | |
Nationality | Other | 6.4 | 1 | 0.8 | 1 | 12.9 | 1 | ||||
Italian | 6.5 | 0.95 | 0.89-1.01 | 0.8 | 0.97 | 0.81-1.15 | 20.9 | 1.52 | 1.46 | 1.59 | |
Education | None/elementary school | 7.7 | 1 | 1.1 | 1 | 20.3 | 1 | ||||
Middle school | 6.9 | 0.99 | 0.90-1.08 | 0.8 | 0.79 | 0.63-0.98 | 17.8 | 0.99 | 0.93 | 1.05 | |
High school | 6.5 | 0.86 | 0.79-0.94 | 0.8 | 0.67 | 0.55-0.83 | 20.4 | 1.04 | 0.99 | 1.10 | |
Bachelor degree | 5.9 | 0.72 | 0.65-0.79 | 0.7 | 0.57 | 0.45-0.72 | 21.8 | 0.97 | 0.92 | 1.02 | |
Other variables | |||||||||||
Multiple pregnancies | No | 6.3 | 1 | 0.8 | 1 | 19.5 | 1 | ||||
Yes | 21.1 | 3.75 | 3.37-4.17 | 0.9 | 1.03 | 0.71-1.50 | 50.9 | 3.91 | 3.65 | 4.19 | |
Parity | Primiparous | 6.7 | 1 | 0.8 | 1 | 21.9 | 1 | ||||
Multiparous | 6.2 | 0.77 | 0.74-0.81 | 0.8 | 0.85 | 0.76-0.95 | 17.3 | 0.63 | 0.61 | 0.64 | |
Previous miscarriages (10 years before) | None | 6.1 | 1 | 0.8 | 1 | 18.7 | 1 | ||||
At least one | 12.5 | 2.02 | 1.90-2.15 | 0.8 | 0.91 | 0.75-1.11 | 35.3 | 2.19 | 2.11 | 2.27 | |
Comorbiditiesb | |||||||||||
Comorbidities | None | 6.4 | 1 | 0.7 | 1 | 19.9 | 1 | ||||
1 | 10.3 | 1.57 | 1.44-1.71 | 1.5 | 2.06 | 1.68-2.51 | 24.4 | 1.18 | 1.11 | 1.24 | |
≥2 | 16.1 | 2.63 | 2.06-3.36 | 4.5 | 6.15 | 4.13-9.15 | 26.4 | 1.28 | 1.07 | 1.54 |