Table 2 Risk factors for AIDS incidence at presentation among patients newly diagnosed with HIV infection
| Â | Number of patients, n | Number of AIDS, n | % | Univariable analysis, crude OR (95% CI) | Multivariable analysis, adjusted OR (95% CI) |
|---|---|---|---|---|---|
Age group | |||||
  ≤ 30 | 11,305 | 1445 | 12.8 | 1.0 (Reference) | 1.0 (Reference) |
 31–40 | 6965 | 1594 | 22.9 | 2.03 (1.87–2.19)*** | 2.76 (2.53–3.01)*** |
 41–50 | 2962 | 886 | 29.9 | 2.91 (2.65–3.21)*** | 4.19 (3.74–4.69)*** |
  ≥ 51 | 1433 | 646 | 45.1 | 5.60 (4.98–6.30)*** | 4.64 (4.00–5.37)*** |
Sex | |||||
 Female | 1580 | 257 | 16.3 | 1.0 (Reference) | 1.0 (Reference) |
 Male | 21,085 | 4314 | 20.5 | 1.32 (1.15–1.52)*** | 1.39 (1.17–1.65)*** |
HIV-transmission route | |||||
 PWID | 6646 | 154 | 2.3 | 1.0 (Reference) | 1.0 (Reference) |
 Bisexual contact | 1898 | 572 | 30.1 | 18.19 (15.08–21.93)*** | 20.28 (16.59–24.79)*** |
 Heterosexual contact | 4152 | 1592 | 38.3 | 26.22 (22.08–31.12)*** | 24.48 (20.39–29.39)*** |
 Homosexual contact | 9779 | 2147 | 22.0 | 11.86 (10.04–14.01)*** | 16.02 (13.35–19.22)*** |
 Othera | 190 | 106 | 55.8 | 53.19 (38.33–73.84)*** | 38.23 (26.94–54.24)*** |
Urbanization | |||||
 Rural | 7384 | 1288 | 17.4 | 1.0 (Reference) | 1.0 (Reference) |
 Urban | 15,281 | 3283 | 21.5 | 1.30 (1.21–1.39)*** | 0.96 (0.88–1.05) |
Income level, n (%) | |||||
 Low | 13,785 | 2328 | 16.9 | 1.0 (Reference) | 1.0 (Reference) |
 Intermediate | 6421 | 1546 | 24.1 | 1.56 (1.45–1.68)*** | 0.99 (0.91–1.07) |
 High | 2459 | 697 | 28.3 | 1.95 (1.76–2.15)*** | 0.85 (0.76–0.94)** |
Cohort period | |||||
 Period 1 | 1373 | 395 | 28.8 | 1.0 (Reference) | 1.0 (Reference) |
 Period 2 | 2262 | 451 | 19.9 | 0.62 (0.53–0.72)*** | 0.65 (0.55–0.77)*** |
 Period 3 | 7774 | 819 | 10.5 | 0.29 (0.25–0.34)*** | 0.87 (0.75–1.01) |
 Period 4 | 5288 | 1274 | 24.1 | 0.79 (0.69–0.90)*** | 1.32 (1.15–1.53)*** |
 Period 5 | 5968 | 1632 | 27.4 | 0.93 (0.82–1.06) | 1.33 (1.15–1.53)*** |
HIV-diagnosis region | |||||
 Taipei area | 7899 | 1656 | 21.0 | 1.0 (Reference) | 1.0 (Reference) |
 Northern Taiwan | 3212 | 608 | 18.9 | 0.88 (0.80–0.98)* | 1.17 (1.05–1.32)** |
 Central Taiwan | 4081 | 839 | 20.6 | 0.98 (0.89–1.07) | 1.25 (1.13–1.39)*** |
 Southern Taiwan | 2687 | 525 | 19.5 | 0.92 (0.82–1.02) | 1.26 (1.11–1.42)*** |
 Kaoping area | 4311 | 817 | 19.0 | 0.88 (0.80–0.97)** | 1.18 (1.06–1.32)** |
 Eastern Taiwan | 475 | 126 | 26.5 | 1.36 (1.10–1.69)** | 1.27 (1.00–1.62)** |
DM | |||||
 No | 22,097 | 4362 | 19.7 | 1.0 (Reference) | 1.0 (Reference) |
 Yes | 568 | 202 | 35.6 | 2.26 (1.90–2.69)*** | 1.04 (0.84–1.29) |
CKD | |||||
 No | 22,358 | 4456 | 19.9 | 1.0 (Reference) | 1.0 (Reference) |
 Yes | 307 | 108 | 35.2 | 2.18 (1.72–2.76)*** | 1.28 (0.96–1.71) |
CHF | |||||
 No | 22,573 | 4522 | 20.0 | 1.0 (Reference) | 1.0 (Reference) |
 Yes | 92 | 42 | 45.7 | 3.50 (2.32–5.27)*** | 1.41 (0.85–2.36) |
COPD | |||||
 No | 22,158 | 4522 | 19.6 | 1.0 (Reference) | 1.0 (Reference) |
 Yes | 507 | 220 | 43.4 | 3.14 (2.62–3.75)*** | 1.63 (1.32–2.01)*** |
Cancer | |||||
 No | 21,019 | 4061 | 19.3 | 1.0 (Reference) | 1.0 (Reference) |
 Yes | 1646 | 503 | 30.6 | 1.85 (1.65–2.06)*** | 1.15 (1.02–1.30)* |
CVD | |||||
 No | 22,408 | 4459 | 19.9 | 1.0 (Reference) | 1.0 (Reference) |
 Yes | 257 | 105 | 40.9 | 2.82 (2.20–3.62)*** | 1.33 (0.97–1.82) |