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Table 1 Sociodemographic, HIV-related variables, and comorbidities in patients newly diagnosed with HIV infection

From: AIDS incidence trends at presentation and during follow-up among HIV-at-risk populations: a 15-year nationwide cohort study in Taiwan

  Period 1 Period 2 Period 3 Period 4 Period 5 Total (n = 22,665) P-value
1/1/1998 to 12/31/2000 (n = 1373) 1/1/2001 to 12/31/2003 (n = 2262) 1/1/2004 to 12/31/2006 (n = 7774) 1/1/2007 to 12/31/2009 (n = 5288) 1/1/2010 to 12/31/2012 (n = 5968)
Follow-up period, median (IQR; years) 2 (1.94) 2 (0.25) 2 (0) 2 (1.75) 2 (1.92) 2 (1.16) < 0.001
Age, mean (IQR; years) 34.56 (11.77) 33.91 (11.66) 33.05 (9.36) 33.17 (10.44) 31.08 (10.26) 32.74 (10.31) < 0.001
Age group, n (%)   < 0.001
  ≤ 30 610 (44.4) 1058 (46.8) 3620 (46.6) 2530 (47.8) 3487 (58.4) 11,305 (49.9)  
 31–40 445 (32.4) 723 (32.0) 2650 (34.1) 1606 (30.4) 1541 (25.8) 6965 (30.7)  
 41–50 165 (12.0) 260 (11.5) 1113 (14.3) 800 (15.1) 624 (10.5) 2962 (13.1)  
  ≥ 51 153 (11.1) 221 (9.8) 391 (5.0) 352 (6.7) 316 (5.3) 1433 (6.3)  
Sex, n (%) < 0.001
 Female 116 (8.5) 117 (5.2) 809 (10.4) 337 (6.4) 201 (3.4) 1580 (7.0)  
 Male 1257 (91.5) 2145 (94.8) 6965 (89.6) 4951 (93.6) 5767 (96.6) 21,085 (93.0)  
Income level, n (%) < 0.001
 Low 805 (58.6) 1352 (59.8) 6147 (79.1) 2737 (51.8) 2744 (46.0) 13,785 (60.8)  
 Intermediate 411 (29.9) 585 (25.8) 1109 (14.3) 1928 (36.5) 2388 (40.0) 6421 (28.3)  
 High 157 (11.4) 325 (14.4) 518 (6.6) 623 (11.7) 836 (14.0) 2459 (10.9)  
Urbanization, n (%) < 0.001
 Rural 265 (19.3) 475 (21.0) 2933 (37.7) 1774 (33.6) 1937 (32.5) 7384 (32.6)  
 Urban 1108 (80.7) 1787 (79.0) 4841 (62.3) 3514 (66.4) 4031 (67.5) 15,281 (67.4)  
HIV-transmission route, n (%) < 0.001
 Homosexual contact 574 (41.8) 1125 (49.7) 1532 (19.7) 2516 (47.6) 4032 (67.6) 9779 (43.2)  
 Heterosexual contact 578 (42.1) 729 (32.2) 974 (12.5) 946 (17.9) 925 (15.5) 4152 (18.3)  
 Bisexual contact 197 (14.4) 278 (12.3) 338 (4.4) 453 (8.6) 632 (10.6) 1898 (8.4)  
 PWID 15 (1.1) 108 (4.8) 4887 (62.9) 1322 (25.0) 314 (5.3) 6646 (29.3)  
 Othera 9 (0.6) 22 (1.0) 43 (0.5) 51 (1.0) 65 (1.1) 190 (0.8)  
Comorbidities, n (%)
 DM 16 (1.2) 60 (2.7) 193 (2.5) 144 (2.7) 155 (2.6) 568 (2.5) < 0.05
 CKD 13 (1.0) 25 (1.1) 94 (1.2) 84 (1.6) 91 (1.5) 307 (1.4) 0.114
 CHF 4 (0.3) 9 (0.4) 23 (0.3) 30 (0.6) 26 (0.4) 92 (0.4) 0.177
 COPD 24 (1.8) 74 (3.3) 173 (2.2) 128 (2.4) 108 (1.8) 507 (2.2) < 0.05
 Cancer 44 (3.2) 129 (5.7) 439 (5.7) 451 (8.5) 583 (9.8) 1646 (7.3) < 0.001
 CVD 12 (0.9) 31 (1.4) 83 (1.1) 74 (1.4) 57 (1.0) 257 (1.1) 0.121
HAART in each cohort period, n (%) 605 (44.1) 1273 (56.3) 1546 (19.9) 1237 (23.4) 2345 (39.3) 7006 (30.9) < 0.001
AIDS incidence in each cohort period, n (%) 438 (31.9) 519 (22.9) 1378 (17.7) 1732 (32.8) 2143 (35.9) 6210 (27.4) < 0.001
 AIDS incidence at presentation, n (%) 395 (90.2) 451 (86.9) 819 (59.4) 1274 (73.6) 1632 (76.2) 4571 (73.6) < 0.001
 AIDS incidence during the follow-up period, n (%) 43 (9.8) 68 (13.1) 559 (40.6) 458 (26.4) 511 (23.8) 1639 (26.4) < 0.001
HIV diagnosis region, n (%) < 0.001
 Taipei area 622 (45.3) 1061 (46.9) 2266 (29.2) 1923 (36.4) 2027 (34.0) 7899 (34.9)  
 Northern Taiwan 161 (11.7) 262 (11.6) 1278 (16.4) 661 (12.5) 850 (14.2) 3212 (14.2)  
 Central Taiwan 238 (17.3) 339 (15.0) 1539 (19.8) 913 (17.3) 1052 (17.6) 4081 (18.0)  
 Southern Taiwan 12 (0.9) 244 (10.8) 1057 (13.6) 593 (11.2) 669 (11.2) 2687 (11.9)  
 Kaoping area 192 (14.0) 307 (13.6) 1535 (19.8) 1086 (20.5) 1191 (20.0) 4311 (19.0)  
 Eastern Taiwan 36 (2.6) 49 (2.2) 99 (1.3) 112 (2.1) 179 (3.0) 475 (2.1)  
  1. Abbreviations: AIDS acquired immunodeficiency syndrome, COPD chronic obstructive pulmonary disease, CHF chronic heart failure, CKD chronic kidney disease, CVD cardiovascular disease, DM diabetes mellitus, HAART highly active antiretroviral therapy, IQR interquartile range, PWID people who injected drugs, SD standard deviation
  2. aIncludes those exposed to blood products, mother-to-child transmission, and unknown exposures