Skip to main content

Table 2 Subgroup analysis of dietary isoflavones intake and gastric cancer risk

From: The association between dietary isoflavones intake and gastric cancer risk: a meta-analysis of epidemiological studies

Subgroup Number of participants Number of studies OR (95% CI) Analysis model Heterogeneity test
I2 (%) P
All studies 596,553 12 0.97 (0.87–1.09) Fixed 27.5 0.174
Study design
 Cohort 592,985 6 0.91 (0.80–1.04) Fixed 15.2 0.316
 Case-control 3568 6 1.15 (0.93–1.43) Fixed 15.4 0.315
Sex
 Male 196,443 4 0.91 (0.78–1.06) Fixed 0 0.576
 Female 397,210 4 0.89 (0.71–1.13) Fixed 34.1 0.208
 Mixed 2900 4 1.25 (0.98–1.59) Fixed 8.6 0.350
Geographic area
 Europe and America 480,212 6 1.11 (0.91–1.34) Fixed 29.2 0.316
 Asia 116,341 6 0.91 (0.79–1.05) Fixed 12.5 0.335
Source of control
 Population 594,898 8 0.98 (0.86–1.11) Fixed 48.5 0.059
 Hospital 1655 4 0.96 (0.73–1.26) Fixed 0 0.663
Sample size
 ≥ 750 595,675 7 0.99 (0.87–1.12) Random 51.9 0.052
 < 750 878 5 0.93 (0.74–1.17) Fixed 0 0.640
Dietary assessment
 > 100 items 595,566 10 0.97 (0.86–1.09) Fixed 37.8 0.107
 ≤ 100 items 987 2 1.02 (0.73–1.44)   0 0.430
Adjustments
 Family history, yes 84,881 2 1.02 (0.85–1.22) Fixed 0 0.737
 No 511,672 10 0.94 (0.82–1.09)   38.6 0.101
 Dietary energy intake, yes 478,967 8 0.98 (0.85–1.12) Random 0 0.868
 No 32,705 4 0.97 (0.79–1.18)   75 0.007