Table 3 Exclusion criteria: presence of specific cardiovascular conditions and non-specific exclusion criteria

List A

Presence of specific cardiovascular conditions

uncontrollable hypertension

decompensated heart failure

severe and symptomatic aortic stenosis

uncontrolled arrhythmia

severe pulmonary hypertension

acute coronary syndromes

acute myocarditis, endocarditis, or pericarditis

aortic dissection

Marfan syndrome

List B

Presence of non-CVD specific exclusion criteria

malignancy (active cancer) or life-threatening disease

bed-bound patient status

participation or plan to participate in other study during trial execution

plan to move during the trial execution