Table 3 Hazard ratios of first events for skirt size in 20s, skirt size at questionnaire completion, BMI and change in skirt size (95% confidence intervals and p values)

Skirt size when aged in 20s

Univariate

1.062 (1.022–1.104)

p = 0.002

Categorical

≤ 16

Reference

≥ 18

1.806 (1.136–2.871)

p = 0.012

Adjusted for smoking, deprivation

≤ 16

Reference

≥ 18

1.681 (1.057–2.675)

p = 0.028

Adjusted for age, smoking, deprivation, hypertension, heart disease, hypercholesterolaemia, stroke, diabetes, rheumatoid arthritis, osteoarthritis, osteoporosis, alcohol abstinence, alcohol ≥21 units/week

≤ 16

Reference

≥ 18

1.390 (0.868–2.226)

p = 0.171

Skirt size at time of questionnaire completion

Univariate

1.091 (1.062–1.121)

p < 0.0005

Categorical

≤ 16

Reference

≥ 18

1.690 (1.342–2.129)

p < 0.0005

Adjusted for smoking, deprivation

≤ 16

Reference

≥ 18

1.579 (1.250–1.995)

p < 0.0005

Adjusted for age, smoking, deprivation, hypertension, heart disease, hypercholesterolaemia, stroke, diabetes, rheumatoid arthritis, osteoarthritis, osteoporosis, alcohol abstinence, alcohol ≥21 units/week

≤ 16

Reference

≥ 18

1.369 (1.071–1.749)

p = 0.012

BMI (kg/m²)

Univariate

1.063 (1.044–1.082)

p < 0.0005

Categorical

<  25

Reference

≥ 25 - < 30

1.461 (1.123–1.899)

p = 0.005

≥ 30

2.308 (1.748–3.047)

p < 0.0005

Adjusted for smoking, deprivation

<  25

Reference

≥ 25 - < 30

1.403 (1.076–1.830)

p = 0.012

≥ 30

2.162 (1.631–2.864)

p < 0.0005

Adjusted for age, smoking, deprivation, hypertension, heart disease, hypercholesterolaemia, stroke, diabetes, rheumatoid arthritis, osteoarthritis, osteoporosis, alcohol abstinence, alcohol ≥21 units/week

<  25

Reference

≥ 25 - < 30

1.353 (1.034–1.770)

p = 0.028

≥ 30

1.880 (1.395–2.533)

p < 0.0005

Change in skirt size/year

Univariate

Categorical

Decrease

Reference

No change

1.554 (0.847–2.850)

p = 0.155

Increase

1.736 (0.994–3.031)

p = 0.052

Adjusted for smoking, deprivation

Decrease

Reference

No change

1.714 (0.915–3.211)

p = 0.092

Increase

1.873 (1.050–3.343)

p = 0.034

Adjusted for age, smoking, deprivation, hypertension, heart disease, hypercholesterolaemia, stroke, diabetes, rheumatoid arthritis, osteoarthritis, osteoporosis, alcohol abstinence, alcohol ≥21 units/week

Decrease

Reference

No change

1.781 (0.950–3.337)

p = 0.072

Increase

1.799 (1.007–3.214)

p = 0.047