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Table 5 Mediation effects by social support in the association of drug use and hazardous drinking with perceived barriers to care and barriers to care in HIV-negative participants

From: Perceived access and barriers to care among illicit drug users and hazardous drinkers: findings from the Seek, Test, Treat, and Retain data harmonization initiative (STTR)

  Perceived access to care Barriers to care
Better condition Higher score Lower score
Illicit drug use
 ACME −0.17 (− 0.35 to 0) 0.06 0.05 (− 0.01 to 0.1) 0.07
 ADE − 1.42 (− 2.33 to − 0.37) < 0.01 0.49 (0.13 to 0.86) 0.02
 Total effects − 1.59 (− 2.58 to − 0.53) < 0.01 0.54 (0.18 to 0.92) 0.01
 Proportion mediated 0.11 (0 to 0.32) 0.07 0.09 (− 0.02 to 0.3) 0.08
Hazardous drinking
 ACME −0.24 (− 0.35 to − 0.15) < 0.01 0.06 (0.04 to 0.09) < 0.01
 ADE −0.34 (− 0.78 to 0.11) 0.18 0.31 (0.17 to 0.45) < 0.01
 Total effects −0.58 (− 1.03 to − 0.13) 0.01 0.38 (0.23 to 0.51) < 0.01
 Proportion mediated 0.42 (0.2 to 1.61) 0.01 0.16 (0.09 to 0.29) < 0.01
  1. All models were adjusted for age, gender, race/ethnicity
  2. ACME Average Causal Mediation Effects, ADE Average direct effect