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Table 3 Combination antiretroviral therapy (cART) regimen and patient biomedical and demographic factors independently associated with the development of diabetes mellitus-related comorbidities (DRCs). Status or event variable†: Diabetes mellitus-related comorbidities (DRCs, N = 531)

From: Relationship between combination antiretroviral therapy regimens and diabetes mellitus-related comorbidities among HIV patients in Gaborone Botswana

Covariates

Proportion Number (%)

Unadjusted

Adjusted

HR

95%CI

HR

95%CI

cART Line1

0318 (59.9.1)

1

–

1

–

cART Line2/3

213 (40.1)

0.49*

0.31–0.79

0.53*

0.33–0.87

CD4–1 > 200 cells/mm3

407 (76.6)

1

–

1

–

CD4–1 ≤ 200 cells/mm3

124 (23.4)

1.6*

1.03–3.2

1.68*

1.03–2.73

Adherence

No

31 (5.8)

1

–

1

–

Yes

478 (90.0)

4.53*

1.42–14.5

3.05©

0.92–10.0

Unknown

22 (4.1)

1.14

0.41–3.12

0.89

0.32–2.51

BMI at cART

Normal Weight

337 (63.5)

1

–

1

–

Under weight

80 (15.1)

0.88

0.46–1.69

0.74

0.37–1.44

Overweight

114 (21.4)

1.6*

1.02–2.61

1.63*

1.07–2.64

Female

368 (69.3)

1

–

1

–

Male

163 (30.7)

0.58*

0.38–0.89

0.49*

0.32–0.77

  1. †likelihood chi-square statistic = 36.25, p = 0.0001; CD4–1 = CD4 at initiation on cART, HR = Hazard ratio, CI = confidence interval, BMI at cART = BMI at initiation on cART, *P < 0.05, ©p = 0.06 (borderline); note that all variables, including age as continuous variable or age groups, that did not achieve p < 0.05 are not included in this model
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BMC Public Health

ISSN: 1471-2458

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