Using a monitoring and evaluation framework to improve study efficiency and quality during a prospective cohort study in infants receiving rotavirus vaccination in El Alto, Bolivia: the Infant Nutrition, Inflammation, and Diarrheal Illness (NIDI) study

Table 1 The NIDI study visit and data collection schedule 2012–2015

Measure	Study Visit (Infant Age in Months)
Target visit schedule	1 (1)	2 (2)	3+ (2)	4 (3)	5 (4)	6 (6–8)	7 (9)	8+ (12–18)
RV^a vaccine criteria	–	–	4 and/or 7 days post RV dose 1	–	–	60 days post RV dose 2	–	–
Maternal Characteristics
Weight and height	X	X		X	X	X	X	X
Clinical and prenatal history	X							X
Prenatal and postpartum micronutrient supplementation	X							X
Two-week morbidity	X	X	X	X	X	X	X	X
Plasma anti-RV IgG^b	X
Plasma ferritin, sTfR^c, CRP^d, AGP^e	X					X
Maternal/Infant SES
Sociodemographic	X							X
Household characteristics	X							X
Infant feeding practices, iron supplementation	X	X	X	X	X	X	X	X
Infant Nutritional & Inflammation Status
Anthropometry	X	X		X	X	X	X	X
Vitamin A, zinc, micronutrient sprinkles supplementation						X		X
Plasma ferritin, sTfR^b, zinc, CRP^d, AGP^e		X				X		X
Infant Infection and Morbidity
Two-week morbidity and diarrhea recall	X	X	X	X	X	X	X	X
Vaccines received						X		X
Fecal RV	X	X	X
Fecal RV and enteric co-pathogens	When diarrhea reported
Outcome: Infant RV Vaccine Immunogenicity
Plasma anti-RV IgG		X				X		X
Plasma anti-RV IgA		X				X		X

ISSN: 1471-2458