Table 1 Marker substances and DDD
| Disease | Marker substances | DDD [mg] |
|---|---|---|
| Tuberculosis [26, 58] | Ethambutol (E) | 1200 |
| Pyrazinamid (Z) | 1500 | |
| Isoniazid (H) | 300 a | |
| Rifampicin (R) | 600 | |
| Protionamide (Pto) | 750 | |
| Terizidone (Trd) | 750 | |
| Rifabutin (Rfb) | 150 | |
| Hepatitis C [27, 58,59,60] | Pegylated interferon-α (PEG-INF) | 0.05, 0.08, 0.1, 0.12, 0.135, 0.15, 0.18 |
| Boceprevir (BOC) | 2400 | |
| Telaprevir (TVR) | 2250 | |
| HIV [25, 58] | Emtricitabin (FTC) | 200 |
| Lamivudin (3TC) | 300 | |
| Opioid dependence [29, 61,62,63,64] | Methadone, | 90 |
| Levomethadone | 45 | |
| Buprenorphine | 8 | |
| Buprenorphine/Naloxone | 8 |