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Table 3 Results of multivariate regression model assessing association between region and use and costs of antineoplastic agents in Taiwan

From: Geographic Variations and Time Trends in Cancer Treatments in Taiwan

Dependent Variable

Independent Variables and Confounders

Unadjusted t

P-value

Adjusted t

P-value

Population adjusted prescription volume of antineoplastic agents per 100,000 people

 

Southern region

reference

 

reference

 
 

Northern region

-1.146

0.281

-0.565

0.602

 

Midwestern region

-10.056

< 0.001

-0.733

0.504

 

Eastern region

-14.653

< 0.001

0.409

0.703

 

Year 2012

reference

 

reference

 
 

Year 2011

-5.676

< 0.001

-1.392

0.236

 

Year 2010

-12.803

< 0.001

-1.264

0.275

 

Year 2009

-21.100

< 0.001

-1.554

0.195

 

Average Age

  

-0.688

0.529

 

% of Male

  

1.367

0.243

 

Population density

  

0.545

0.615

 

Physician density

  

0.593

0.585

 

Cancer incidence

  

-0.055

0.959

Population adjusted cost of antineoplastic agents per 100,000 people

 

Southern region

reference

 

reference

 
 

Northern region

-0.703

0.500

-5.797

0.004

 

Midwestern region

-4.448

0.002

- 4.963

0.008

 

Eastern region

-12.106

<0.001

- 5.519

0.005

 

Year 2012

reference

 

reference

 
 

Year 2011

-4.831

0.001

-8.271

0.001

 

Year 2010

-10.996

<0.001

-7.521

0.002

 

Year 2009

-19.753

<0.001

-10.691

<0.001

 

Average Age

  

8.024

0.001

 

% of Male

  

9.665

0.001

 

Population density

  

6.092

0.004

 

Physician density

  

-1.154

0.313

 

Cancer incidence

  

2.032

0.112

Population adjusted prescription volume of TT per 100,000 people

 

Southern region

reference

 

reference

 
 

Northern region

-0.811

0.438

-0.726

0.508

 

Midwestern region

-3.498

0.007

-0.107

0.920

 

Eastern region

-6.858

<0.001

0.567

0.601

 

Year 2012

reference

 

reference

 
 

Year 2011

-5.674

<0.001

-2.343

0.079

 

Year 2010

-9.248

<0.001

-1.388

0.238

 

Year 2009

-11.659

<0.001

-1.247

0.281

 

Average Age

  

-0.389

0.717

 

% of Male

  

2.893

0.044

 

Population density

  

0.739

0.501

 

Physician density

  

0.838

0.449

 

Cancer incidence

  

-0.030

0.978

Population adjusted Cost of TT per 100,000 people

 

Southern region

reference

 

reference

 
 

Northern region

-0.467

0.652

-0.760

0.490

 

Midwestern region

-2.957

0.016

-0.338

0.752

 

Eastern region

-5.631

<0.001

0.489

0.650

 

Year 2012

reference

 

reference

 
 

Year 2011

-5.320

<0.001

-3.813

0.019

 

Year 2010

-8.603

<0.001

-2.238

0.089

 

Year 2009

-12.036

<0.001

-2.323

0.081

 

Average Age

  

0.512

0.635

 

% of Male

  

4.335

0.012

 

Population density

  

0.784

0.477

 

Physician density

  

1.213

0.292

 

Cancer incidence

  

-0.800

0.469

  1. TT targeted therapies; Average Age = average age of cancer patients; % of Male = percentage of male cancer patients; Population density = number of population divided by geographic area; Physician density = number of physician divided by number of population in that region per 100,000 people; bold and italic = significant