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Table 2 Hazard Ratios for Alcohol-Attributable Disease Categories in 12,300,516 Men (French National Hospital Discharge database 2008–2012)

From: Alcohol use disorders and associated chronic disease – a national retrospective cohort study from France

Alcohol-Attributable Disease Category Total, n (%) AUDs, n (%) Mean (SD) age at incidence Hazard Ratio with AUDs (95% CI)
AUDs No AUDs
Liver diseases
 Cirrhosis 357,809 (2.91) 155,000 (43.3) 59.6 (12.0) 64.9 (16.6) 15.97 (15.86–16.09)
 Liver cancer 56,162 (0.46) 26,199 (46.7) 65.3 (9.9) 69.6 (12.4) 16.12 (15.84–16.40)
Pancreatic diseases
 Acute pancreatitis 80,860 (0.66) 32,711 (40.5) 48.8 (13.2) 60.7 (18.0) 12.14 (11.96–12.32)
 Chronic pancreatitis 57,465 (0.47) 31,602 (55.0) 53.2 (12.3) 62.3 (16.1) 20.36 (20.01–20.71)
 Pancreatic cancer 41,853 (0.34) 3659 (8.7) 62.2 (10.9) 68.6 (12.0) 1.61 (1.56–1.67)
Upper aerodigestive tract cancers
 Head and neck cancer 82,852 (0.67) 19,875 (24.0) 57.8 (8.7) 63.2 (11.9) 4.39 (4.31–4.46)
 Larynx cancer 37,952 (0.31) 8399 (22.1) 59.0 (8.9) 64.9 (11.1) 4.03 (3.93–4.14)
 Oesophageal cancer 36,083 (0.29) 6084 (16.9) 60.7 (9.4) 66.8 (11.5) 3.19 (3.10–3.28)
Colorectal cancer 190,593 (1.55) 10,427 (5.5) 65.7 (10.3) 69.5 (12.2) 1.14 (1.11–1.16)
Cardiovascular diseases
 Ischemic heart disease 1,290,533 (10.49) 71,137 (5.5) 62.6 (11.5) 68.8 (12.8) 1.11 (1.10–1.12)
 Congestive heart failure 980,140 (8.0) 76,602 (7.8) 64.4 (12.1) 73.4 (12.8) 1.95 (1.94–1.97)
 Atrial fibrillation 898,455 (7.30) 54,639 (6.1) 67.5 (11.5) 74.4 (11.9) 1.64 (1.63–1.66)
 Ischemic stroke 432,393 (3.52) 34,288 (7.9) 63.8 (11.4) 71.3 (13.0) 1.75 (1.73–1.77)
 Haemorrhagic and other non-ischemic stroke 108,219 (0.88) 12,164 (11.2) 59.6 (12.7) 67.9 (16.9) 2.23 (2.19–2.28)
Dementia 389,687 (3.17) 47,349 (12.2) 65.6 (13.2) 80.5 (9.1) 4.67 (4.63–4.72)
Infectious diseases
 Pneumococcal pneumonia 28,569 (0.23) 4799 (16.8) 56.4 (12.9) 64.7 (18.6) 3.71 (3.60–3.83)
 Tuberculosis 42,945 (0.35) 4524 (10.5) 57.4 (13.3) 61.8 (20.3) 2.22 (2.15–2.29)
Injuries
 Non-intentional injury 357,461 (2.91) 42,425 (11.9) 56.7 (15.6) 56.5 (24.1) 3.11 (3.08–3.15)
 Self-harm 144,723 (1.18) 36,548 (25.3) 43.1 (12.0) 39.4 (17.1) 6.55 (6.47–6.64)
 Other intentional injury 32,113 (0.26) 5966 (18.6) 43.7 (21.9) 36.7 (18.3) 5.02 (4.88–5.17)