Table 1 Algorithms used to define the 16 conditions

1

Diabetes

Physical

All persons included in the Danish Diabetes Register where the inclusion date is before the population date (1/1 2012) [22]

2

Cancer

Physical

C00-C43 or C45-C97

(DIAG) ^a

3

Back pain

Physical

M40–54

(DIAG) ^a

4

Osteoarthritis

Physical

M15-M19

(DIAG) ^a

5

Osteoporosis

Physical

M80-M82and/or for persons aged 45 years and older contacts with the ICD-10 codes S22.0, S22.1, S32.0, S32.7, S32.8, S42.2, S42.3, S42.4, S42.7, S42.8, S42.9, S52.5, S52.6, S52.7, S52.8, S52.9, S62.0, S62.1, S72

(DIAG) ^a and/or (MEDICINE) ^b all medicine prescriptions with either ATC: M05B, G03XC01, H05AA02, H05AA03

6

Joint disease

Physical

M05, M06.0, M06.8, M07.0, M07.1, M07.3, M10.0, M10.9

(DIAG) ^a

7

Allergies

Physical

J30 except J30.0

(DIAG) ^a and/or (MEDICINE) ^b all medicine prescriptions with either ATC: V01AA02, V01AA03; V01AA05, V01AA11; R01AC, R01AD, R06A, S01G, R01BA52.

8

Chronic obstructive pulmonary disease (COPD)

Physical

J40, J41, J42, J43, J44, J47, J96

(DIAG) ^a All patients of minimum 35 years of age at contact. And/or (MEDICINE1) ^b all medicine prescriptions with either ATC: R03AC, R03AK, R03BA, R03BB, R03CC, R03DA, R03DC, V03AN01. And/or (SERVICE10) ^c if patients have had a minimum of two lab services within the last 12 months. Lab services (80) 7113 (lung spirometer test), (80) 7121 (lung function test). MEDICINE and SERVICES are ignored if there are contacts with J45 or J46 diagnosis.

9

Dementia

Mental health

F00, G30, F01, F02.0, F03.9, G31.8B, G31.8E, G31.9, G31.0B

(DIAG) ^a All patients of minimum 60 years of age at contact and/or (MEDICINE) ^b all medicine with the prescriptions with the ATC N06D also for patients of minimum 60 years of age.

NB: Only one prescription (in contrast to two in the other algorithms)

10

Schizophrenia

Mental health

F20, F21, F22, F25, F28, F29, F31

(DIAG) ^a and/or (MEDICINE) ^b all medicine prescriptions with either ATC: N05AX13, N05AX12, N05AH03, N05AX13, N05Ax08

NB: Only A-diagnosis not B-diagnosis

11

Long term use of antidepressants

Mental health

(MEDICINE) ^b At least three medicine prescriptions with the ATC N06A.

NB: At least three prescriptions (instead of two) on deferent dates within the latest five year with at least 730 days (2 years) between the first and the last one.

Patients with a schizophrenia diagnosis or with a dementia diagnosis are excluded from this algorithm.

12

Anxiety

Mental health

F40.1, F41.1

(DIAG) ^a and (MEDICINE) ^b At least three medicine prescriptions with the ATC N06A.

NB: At least three prescriptions (instead of two) on deferent dates within the latest five year with at least 730 days (2 years) between the first and the last one.

Patients with a depression diagnosis are excluded from this algorithm

13

High cholesterol

Physical

E78.0, E78.2, E78.4, E78.5

(DIAG) ^a and/or (MEDICINE) ^b all medicine prescriptions with the ATC C10

14

Hypertension

Physical

I10, I11, I12, I13, I15

(DIAG) ^a and (MEDICINE) ^b all medicine prescriptions with either ATC: C07B, C03A, C03B, C03E, C03X and/or (MEDICINE) ^b all medicine prescriptions with either ATC: C03C, C03D, C07A, C09 IF the person DOES NOT have hospital or outpatient contact with the ICD-10 codes I20.0, I21, I25.1, I50 and/or two medicine prescriptions with ATC: C08 IF the person DOES NOT have a hospital or outpatient contact with the ICD-10 codes I20-I25

15

Stroke

Physical

G45, G46, I60, I61, I62, I63, I64, I65, I66, I67, I68, I69

(DIAG) ^a

16

Heart disease

Physical

I20, I21, I23, I24, I25, I50, I11, I13

(DIAG) ^a and/or (MEDICINE) ^b all medicine prescriptions with either ATC: C01A, C01B, C01D, C01E