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Table 1 Cardiovascular Disease and Mortality Outcomes Ascertainment in WHI

From: The Objective Physical Activity and Cardiovascular Disease Health in Older Women (OPACH) Study

Study Outcome Definition and Confirmation of Outcomes
Non-fatal myocardial infarction Standardized criteria for diagnostic electrocardiography changes, elevated cardiac enzymes or both
Revascularization Documentation of the procedure in the medical record.
Angina Hospital record, angiography evidence, diagnostic stress test, or documented physician diagnosis and medical treatment
Congestive heart failure Hospital record and diagnostic confirmatory tests
Fatal coronary heart disease Documentation in the hospital record, autopsy report or cause of death on the death certificate with evidence of previous coronary heart disease
Stroke Documentation in the medical record of neurologic deficit of rapid onset consistent with stroke and lasting for at least 24 h or until death
Death from other cardiovascular disease Confirmatory evidence in the medical records as ascertained by physician adjudicators