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Table 2 ICER league table using iterative optimisation routine

From: Designing an optimal HIV programme for South Africa: Does the optimal package change when diminishing returns are considered?

Intervention

Total cost over 20 years (2014 USD)

Life years saved over rolling baseline

Incremental cost over rolling baseline (2014 USD)

ICER (Cost/LYS)

Final rank

Baseline

52,533,337,028

-

-

-

-

Condom availability Max

51,022,627,998

3,899,254

−1,510,709,029

Cost-saving

1

MMC Max

51,014,858,122

951,825

−7,769,876

Cost-saving

2

SBCC1 B + 1

51,026,339,070

320,591

11,480,948

36

Superseded

ART (current guidelines) Max

51,243,805,676

2,004,044

217,466,606

109

3

PMTCT Max

51,314,427,752

497,889

70,622,076

142

4

Infant testing at 6 weeks B + 3

51,343,303,114

116,406

28,875,362

248

Superseded

Infant testing at 6 weeks Max

51,352,292,109

36,216

8,988,995

248

5

Universal ART Max

52,658,690,554

5,241,734

1,306,398,445

249

6

General population HCT B-2

52,002,826,154

−1,313,947

−655,864,400

499

Superseded

General population HCT B-1

52,338,752,835

738,355

335,926,681

455

Superseded

SBCC1 B + 2

52,406,222,629

111,661

67,469,794

604

Superseded

General population HCT B + 1

53,032,457,662

1,012,981

626,235,033

618

Superseded

SBCC1 B + 3

53,098,136,663

90,853

65,679,001

723

Superseded

SBCC1 Max

53,165,119,118

89,429

66,982,455

749

7

General population HCT B + 2

53,462,915,656

349,206

297,796,538

853

Superseded

General population HCT B + 3

53,755,702,602

285,671

292,786,946

1025

Superseded

SBCC2 B + 2

53,778,290,385

18,820

22,587,782

1200

Superseded

SBCC2 Max

53,777,167,130

37,516

−1,123,255

Cost-saving

8

General population HCT Max

54,066,875,384

234,391

289,708,254

1236

9

SBCC3 B-3

53,986,493,432

−50,161

−80,381,952

1602

Superseded

SBCC3 Max

54,236,500,801

137,678

250,007,369

1816

10

HCT for sex workers Max

54,277,669,534

15,576

41,168,734

2643

11

Infant testing at birth B + 2

54,547,672,527

91,981

270,002,992

2935

Superseded

Infant testing at birth B + 3

54,686,528,178

47,297

138,855,651

2936

Superseded

Infant testing at birth Max

54,817,666,909

44,648

131,138,732

2937

12

PrEP for sex workers Max

55,022,116,749

20,554

204,449,839

9947

13

Testing adolescents B + 1

55,538,796,938

31,920

516,680,189

16,187

Superseded

Testing adolescents B + 2

56,378,936,369

48,428

840,139,431

17,348

Superseded

Testing adolescents B + 3

57,309,365,304

48,915

930,428,935

19,021

Superseded

Testing adolescents Max

57,956,976,545

33,142

647,611,241

19,540

14

PrEP for young women Max

68,668,523,964

406,120

10,711,547,418

26,375

15

Early infant male circumcision B + 1

68,755,214,097

2

86,690,134

43,345,067

Superseded

Early infant male circumcision Max

69,024,142,290

3

268,928,193

89,642,731

16