BMI and waist circumference cut-offs for corresponding levels of insulin sensitivity in a Middle Eastern immigrant versus a native Swedish population – the MEDIM population based study

Bennet, Louise; Stenkula, Karin; Cushman, Samuel W; Brismar, Kerstin

doi:10.1186/s12889-016-3892-1

Table 2 Association between insulin sensitivity index (ISI) and type 2 diabetes related risk factors in Iraqi and Swedish born participants in the MEDIM study 2010 to 2012

From: BMI and waist circumference cut-offs for corresponding levels of insulin sensitivity in a Middle Eastern immigrant versus a native Swedish population – the MEDIM population based study

Risk factors	Total male study population			Interaction with Iraqi ancestry	Men born in Sweden			Men born in Iraq¹
	N = 840 (R² = 0.37)			Interaction with Iraqi ancestry	N = 293 (R² = 0.46)			N = 547 (R² = 0.28)
	β	95% CI		P _interaction	β	95% CI		β	95% CI
Born in Sweden	Reference
Born in Iraq	−.102^***	−.133	−.071	−	−			−
Body mass index (kg/m²), per 1 SD	−.053^***	−.082	−.025	0.001	−.108^***	−.153	−.062	NS
Waist circumference (cm), per 1 SD	−.077^***	−.106	−.049	0.026	−.059^**	−.104	−.015	−.112^***	−.132	−.093
Plasma triglycerides (mmol/L), per 1 SD	−.039^***	−0.54	−.024	0.042	−.056^***	−.082	−.030	−.031^***	−.050	−.012
Plasma HDL (mmol/L), per 1 SD	.021^**	.005	0.37	NS	NS			.022^**	.002	.042
Physical activity (hours/week), per 1 SD	.034^***	.019	.049	NS	.045^***	.021	.069	.027^**	.008	.045
Current tobacco smoking								NS
− No	Reference				Reference
− Yes	.034^**	.002	.066	NS	NS
First-degree Family History of Diabetes
− No	Reference							Reference
− Yes	−.036^***	−.067	−0.006	NS	NS			−.045^**	−.082	−.009
Risk factors	Total female study population			Interaction with Iraqi ancestry	Females born in Sweden			Females born in Iraq¹
Risk factors	N = 628 (R² = 0.39)			Interaction with Iraqi ancestry	N = 245 (R² = 0.41)			N = 383 (R = 0.32)
Born in Sweden	Reference
Born in Iraq	−.141^***	−.174	−.107	−	−			−
Body mass index (kg/m²), per 1 SD	−.030^*	−.060	−.001	NS	NS			−.039^*	−.078	−.001
Waist circumference (cm), per 1 SD	−.090^***	−.120	−.059	NS	−.126^***	−.155	−.096	−.085^***	−.123	−.047
Plasma triglycerides (mmol/L), per 1 SD	−.052^***	−0.72	−.033	NS	−.061^***	−.092	−.030	−.061^***	−.078	−.001
Plasma HDL (mmol/L), per 1 SD	.022^**	.004	.040	NS	NS			NS
Physical activity (hours/week), per 1 SD	.018^*	.001	.034	NS	NS			.027^**	.005	.050

Data assessed by multivariate linear regression presented as the last step in backward elimination, entry and removal of covariates at p ≤ 0.05 and p ≤ 0.1. Models adjusted for being born in Iraq (the non-stratified total models), age, male gender (non-stratified models), body mass index, waist circumference, plasma triglycerides, plasma high density lipoprotein, high sensitive C-reactive protein, physical activity, current tobacco smoking, family history of diabetes in first degree relatives, economic difficulties. ¹ For Iraqi born time since migration was also included as a covariate in the analysis
Regression coefficients (β) for the continuous independent variables, were standardised to a unit variance (per 1 standard deviation (SD) in the strata of ethnicity and gender
Interactions with country of birth were considered only when the included marginal effects were significant
Variance inflation factor (VIF) <1.5
^***p ≤ 0.001; ^**p ≤ 0.010; ^*p ≤ 0.050
Data presented for the total study population and for males and females separately
Data assessed by multivariate linear regression displaying β coefficients with 95% confidence intervals with ISI as the dependent variable

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ISSN: 1471-2458

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