Skip to main content

Table 4 Results of Cox regression analysis for hospitalization in patients diagnosed with influenza in the 2013/2014 season

From: Factors associated with hospitalization for seasonal influenza in a Japanese nonelderly cohort

  Univariate Analysis Multivariable analysis
HR 95.0 % CI P HR 95.0 % CI P
Female 1.31 1.01 to 1.68 0.039 1.26 0.98 to 1.63 0.075
Age, (years)
 18–64 Ref.   <0.001 Ref.   <0.001
 <2 10.46 7.38 to 14.81 <0.001 12.02 8.07 to 17.91 <0.001
 2–4 3.32 2.31 to 4.79 <0.001 3.82 2.52 to 5.82 <0.001
 5–17 1.02 0.72 to 1.43 0.924 1.31 0.90 to 1.91 0.155
Comorbidity
 Asthma 2.27 1.76 to 2.94 <0.001 1.24 0.93 to 1.66 0.139
 COPD 5.72 2.70 to 12.14 <0.001 4.09 1.84 to 9.09 0.001
 Cerebrovascular disease 3.08 0.99 to 9.62 0.053 2.28 0.70 to 7.47 0.173
 Diabetes mellitus 1.74 0.65 to 4.69 0.270 1.77 0.63 to 4.99 0.282
 Mental disorder 1.97 1.27 to 3.06 0.002 1.58 0.96 to 2.59 0.074
 Neurologic disease 2.32 1.54 to 3.48 <0.001 2.39 1.45 to 3.94 0.001
 Anemia 2.62 1.47 to 4.68 0.001 1.77 0.95 to 3.29 0.072
 Liver disease 1.25 0.56 to 2.82 0.586 0.90 0.38 to 2.15 0.816
 Dialysis 20.76 2.91 to 147.95 0.002 9.34 1.18 to 74.03 0.034
 Malignancy 2.70 1.00 to 7.24 0.049 2.00 0.71 to 5.65 0.192
 Regular steroid use 3.29 1.55 to 6.98 0.002 2.58 1.18 to 5.64 0.018
Respiratory co-infection 1.32 0.99 to 1.77 0.057 1.10 0.82 to 1.48 0.509
Virus type
 A Ref.   <0.001 Ref.   0.002
 B 0.65 0.49 to 0.86 0.002 0.73 0.55 to 0.97 0.028
 Both A and B 2.62 1.38 to 4.97 0.003 2.23 1.17 to 4.26 0.015
  1. COPD chronic obstructive pulmonary disease