Table 3 Results of Cox regression analysis for hospitalization in patients diagnosed with influenza
From: Factors associated with hospitalization for seasonal influenza in a Japanese nonelderly cohort
Univariate Analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
HR | 95.0 % CI | P | HR | 95.0 % CI | P | |
Female | 1.30 | 1.03 to 1.65 | 0.029 | 1.26 | 0.99 to 1.59 | 0.059 |
Age, (years) | ||||||
18–64 | Ref. | <0.001 | Ref. | <0.001 | ||
<2 | 9.69 | 6.94 to 13.53 | <0.001 | 12.25 | 8.37 to 17.93 | <0.001 |
2–4 | 3.58 | 2.56 to 5.00 | <0.001 | 4.56 | 3.10 to 6.72 | <0.001 |
5–17 | 1.05 | 0.77 to 1.43 | 0.757 | 1.45 | 1.03 to 2.05 | 0.033 |
Comorbidity | ||||||
Asthma | 2.12 | 1.66 to 2.70 | <0.001 | 1.15 | 0.88 to 1.51 | 0.309 |
COPD | 5.79 | 2.87 to 11.70 | <0.001 | 3.71 | 1.75 to 7.88 | 0.001 |
Cerebrovascular disease | 3.59 | 1.34 to 9.64 | 0.011 | 2.48 | 0.88 to 6.97 | 0.084 |
Diabetes mellitus | 2.37 | 1.05 to 5.32 | 0.037 | 2.18 | 0.92 to 5.19 | 0.076 |
Mental disorder | 1.93 | 1.28 to 2.92 | 0.002 | 1.41 | 0.89 to 2.25 | 0.144 |
Neurologic disease | 2.56 | 1.78 to 3.68 | <0.001 | 2.62 | 1.68 to 4.11 | <0.001 |
Anemia | 2.82 | 1.67 to 4.74 | <0.001 | 1.90 | 1.09 to 3.31 | 0.024 |
Liver disease | 2.02 | 1.10 to 3.69 | 0.023 | 1.47 | 0.76 to 2.83 | 0.255 |
Dialysis | 16.09 | 2.26 to 114.66 | 0.006 | 5.87 | 0.77 to 44.89 | 0.088 |
Malignancy | 3.53 | 1.57 to 7.93 | 0.002 | 2.29 | 0.96 to 5.43 | 0.061 |
Regular steroid use | 3.22 | 1.60 to 6.51 | 0.001 | 2.35 | 1.12 to 4.91 | 0.024 |
Respiratory co-infection | 1.26 | 0.97 to 1.65 | 0.082 | 1.06 | 0.81 to 1.38 | 0.689 |
Virus type | ||||||
A | Ref. | <0.001 | Ref. | 0.002 | ||
B | 0.71 | 0.54 to 0.92 | 0.009 | 0.73 | 0.55 to 0.96 | 0.025 |
Both A and B | 2.80 | 1.48 to 5.28 | 0.002 | 2.21 | 1.16 to 4.22 | 0.016 |
Season | ||||||
2013/2014 | Ref. | Ref. | ||||
2014/2015 | 0.83 | 0.59 to 1.17 | 0.283 | 0.82 | 0.57 to 1.17 | 0.267 |