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Table 1 Clinical characteristics of patients diagnosed with influenza

From: Factors associated with hospitalization for seasonal influenza in a Japanese nonelderly cohort

 

Total

2013/2014 season

2014/2015 season

Parameters

Non-hospitalized patient

Hospitalized patient

P

Non-hospitalized patient

Hospitalized patient

P

Non-hospitalized patient

Hospitalized patient

P

 

No.

(%)

No.

(%)

 

No.

(%)

No.

(%)

 

No.

(%)

No.

(%)

 

Number of patients

87,778

 

276

  

74,101

 

239

  

13,677

 

37

  

 Female, n (%)

39,122

(44.57)

141

(51.09)

0.034

32,896

(44.39)

122

(51.05)

0.045

6226

(45.52)

19

(51.35)

0.585

 Age, (years)

    

<0.001

 

0.00

  

<0.001

     

  <2

2916

(3.32)

58

(21.01)

 

2553

(3.45)

56

(23.43)

 

363

(2.65)

2

(5.41)

 

  2–4

7932

(9.04)

58

(21.01)

 

6934

(9.36)

48

(20.08)

 

998

(7.30)

10

(27.03)

 

  5–17

35,066

(39.95)

75

(27.17)

 

29,397

(39.67)

62

(25.94)

 

5669

(41.45)

13

(35.14)

 

  18–64

41,864

(47.69)

85

(30.80)

 

35,217

(47.53)

73

(30.54)

 

6647

(48.60)

12

(32.43)

 

Virus type

    

<0.001

 

0.00

  

<0.001

    

0.769

 A

54,643

(62.25)

188

(68.12)

 

41,160

(55.55)

152

(63.60)

 

13,483

(98.58)

36

(97.30)

 

 B

32,048

(36.51)

78

(28.26)

 

31,863

(43.00)

77

(32.22)

 

185

(1.35)

1

(2.70)

 

 Both A and B

1030

(1.17)

10

(3.62)

 

1021

(1.38)

10

(4.18)

 

9

(0.07)

0

(0.00)

 

 Unknown

57

(0.06)

0

(0.00)

 

57

(0.08)

0

(0.00)

 

0

(0.00)

0

(0.00)

 

Comorbidity

 Asthma

20,631

(23.50)

109

(39.49)

<0.001

17,536

(23.66)

99

(41.42)

<0.001

3095

(22.63)

10

(27.03)

0.659

 COPD

444

(0.51)

8

(2.90)

<0.001

382

(0.52)

7

(2.93)

<0.001

62

(0.45)

1

(2.70)

0.422

 Cardiovascular disease

811

(0.92)

5

(1.81)

0.222

705

(0.95)

5

(2.09)

0.14

106

(0.78)

0

0.00

1.000

 Cerebrovascular disease

357

(0.41)

4

(1.45)

0.025

304

(0.41)

3

(1.26)

0.126

53

(0.39)

1

(2.70)

0.352

 Diabetes mellitus

811

(0.92)

6

(2.17)

0.065

711

(0.96)

4

(1.67)

0.425

100

(0.73)

2

(5.41)

0.019

 Mental disorder

4294

(4.89)

25

(9.06)

0.002

3618

(4.88)

22

(9.21)

0.003

676

(4.94)

3

(8.11)

0.612

 Neurologic disease

4425

(5.04)

33

(11.96)

<0.001

3708

(5.00)

26

(10.88)

<0.001

717

(5.24)

7

(18.92)

0.001

 Anemia

1749

(1.99)

15

(5.43)

<0.001

1458

(1.97)

12

(5.02)

0.002

291

(2.13)

3

(8.11)

0.052

 Immunodeficiency

113

(0.13)

1

(0.36)

0.811

97

(0.13)

1

(0.42)

0.741

16

(0.12)

0

0.00

1.000

 Liver disease

1768

(2.01)

11

(3.99)

0.035

1494

(2.02)

6

(2.51)

0.755

274

(2.00)

5

(13.51)

<0.001

 Dialysis

19

(0.02)

1

(0.36)

0.08

14

(0.02)

1

(0.42)

0.039

5

(0.04)

0

0.00

1.000

 Malignancy

547

(0.62)

6

(2.17)

0.004

464

(0.63)

4

(1.67)

0.102

83

(0.61)

2

(5.41)

0.008

 Regular steroid use

796

(0.91)

8

(2.90)

0.002

665

(0.90)

7

(2.93)

0.003

131

(0.96)

1

(2.70)

0.808

Complication

 Respiratory co-infection

59,597

(67.90)

201

(72.83)

0.092

50,589

(68.27)

177

(74.06)

0.064

9008

(65.86)

24

(64.86)

1.000

 Encephalitis

0

(0.00)

6

(2.17)

<0.001

0

(0.00)

6

(2.51)

<0.001

0

(0.00)

0

(0.00)

 Pneumonia

0

(0.00)

6

(2.17)

<0.001

0

(0.00)

4

(1.67)

<0.001

0

(0.00)

2

(5.41)

<0.001

 Death

0

(0.00)

1

(0.36)

<0.001

0

(0.00)

1

(0.42)

<0.001

0

(0.00)

0

(0.00)

  1. COPD chronic obstructive pulmonary disease