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Table 1 Summary of studies investigating the occurrence of brucellosis in humans in Kenya deemed as relevant to be included in this systematic review

From: Systematic review of brucellosis in Kenya: disease frequency in humans and animals and risk factors for human infection

Population

County

Diagnostic test

Complementary tests

Study outcome

Ref

Diseases frequencya

Risk factor

Apparently healthy

National

ELISA

NA

3 (1.0–5.0)

Yes

[24]

Nairobi

Central

Coast

Eastern

N/eastern

Nyanza

Rift Valley

Western

NA

0

1.1 (0.0–2.7)

1.0 (0.0–2.9)

1.5 (0.0–4.3)

10.3 (0.0–21.8)

0

2.8 (0.0–7.0)

0.5 (0.0–1.6)

Apparently healthy

Kiambu

Kajiado

Marsabit

ELISA

NA

2.4 (1.9–30)

15.3 (10.5–21.8)

46.5 (39.0–54.1)

Yes

[32]

Outbreak patients

Garissa

RBT/BMAT

ELISA,CFT

5 of 12 outbreak cases

No

[17]

Hospital patients

Narok

RBT

NA

21.2 (13.8–35.9)

No

[23]

Hospital patients

Machakos

RBT

SAT

39 patients case series report

No

[25]

Hospital patients

Machakos

RBT

CFT,SAT

10.4 b

No

[26]

Hospital patients

Garissa

RBT

PCR

31.8 b

Yes

[21]

High risk pastoralist population

Isiolo

QS

NA

QS

Yes

[33]

Hospital patients

Nairobi

RBT

ELISA

5 (1.4–9.4)

No

[22]

Hospital patients

Nairobi

ELISA

Isolation

2 BM isolates and 21 seropositive from study cohort

No

[27]

High risk pastoralist population

Turkana

RBT

ELISA

17 (13.1–22.4)

Yes

[30]

Hospital patients

NS

RBT

Isolation

70 isolates (64BM,6BA) from case reports

No

[29]

Hospital patients

NS

Isolation

NA

1 BA isolate

from a case report

No

[19]

Hospital patients

Kiambu

Narok

RBT/SAT

IFA

3.2 (1.1–4.5)

14.4 (8.0–18.9)

No

[31]

High risk occupational groups

Nairobi

Naivasha

SAT

NA

2 (0.5–4.5)

7 (4.1–14.6)

No

[20]

High risk pastoralist population

Marsabit

QS

NA

QS

Yes

[34]

High risk occupational groups

Busia

RBT

NA

0.1 (0.007–0.8)

No

[18]

Hospital patients

Busia

RBT

BPAT, Coombs, SAT

0.6 (0.04–0.9)

NO

[28]

  1. aSeroprevalence estimates (bold) with the corresponding 95 % Confidence Intervals or outcome from outbreak investigation/case reports/case series
  2. b95 % Confidence Interval not provided, NA not available, Ref reference, BA B. abortus, BM B. melitensis, ELISA enzyme-linked immunosorbent assay, RBT rose bengal plate test, SAT serum agglutination test, CFT complement fixation test, IFA immuno fluorescence antibody assay, BMAT Brucella micro-agglutination test, NS not specified, QS qualitative studies without laboratory investigations (Cases defined as individuals diagnosed and treated for brucellosis in the past one year)