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Table 1 Characteristics of subjects at enrolment according to late presentation

From: The risk of late or advanced presentation of HIV infected patients is still high, associated factors evolve but impact on overall mortality is vanishing over calendar years: results from the Italian MASTER Cohort

Subjects’ characteristics

No

Yes

Total

P value

n (%)*

n (%)a

n (%)b

Total

8905

10486

19391

 

Gender

 Male

6477 (44.7)

8022 (55.3)

14499 (74.8)

<0.001

 Female

2428 (49.6)

2464 (50.4)

4892 (25.2)

Age at enrolment (years)

  < 25

1869 (71.9)

729 (28.1)

2598 (13.4)

<0.001

 25–34

4362 (49.3)

4478 (50.7)

8840 (45.6)

 35–44

1863 (36.2)

3290 (63.9)

5153 (26.6)

 45–54

602 (30.8)

1355 (69.2)

1957 (10.1)

  ≥ 55

209 (24.8)

634 (75.2)

843 (4.3)

Mean age, years (SD)

32.1 (8.9)

37.0 (9.9)

34.8 (9.8)

<0.001

Mean CD4 T+ cell count//mm3 (SD)

644.4 (275)

171.1 (137.4)

403.1 (320.4)

<0.001

Period of enrolment

 1985–1991

2612 (60.8)

1681 (39.2)

4293 (22.1)

<0.001

 1992–1997

2010 (41.3)

2855 (58.7)

4865 (25.1)

 1998–2003

1727 (40.6)

2528 (59.4)

4255 (21.9)

 2004–2009

1642 (42.5)

2217 (57.5)

3859 (19.9)

 2010–2013

914 (43.1)

1205 (56.9)

2119 (10.9)

Country of origin

 Availableb

8738 (98.1)

10210 (97.4)

18948 (97.7)

<0.001

 Italy

7996 (47.1)

8991 (52.9)

16987 (89.4)

 Others

742 (37.8)

1219 (62.2)

1961 (10.3)

HIV exposure category

 Availableb

8156 (91.6)

9528 (90.9)

17684 (91.2)

<0.001

 MSM

1333 (47.8)

1455 (52.2)

2788 (15.8)

 IDUs

3879 (51.5)

3654 (48.5)

7533 (42.6)

 Heterosexuals

2337 (39.2)

3620 (60.8)

5957 (33.7)

 MSM-IDUs

60 (57.1)

45 (42.9)

105 (0.6)

 Heterosexuals-IDUs

256 (41.0)

368 (59.0)

624 (3.5)

 Haemophilia/Perinatal transmission

26 (53.1)

23 (46.9)

49 (0.3)

 Unknown

32 (48.5)

34 (51.5)

66 (0.4)

 Others

233 (41.5)

329 (58.5)

562 (3.2)

Viral load at enrolmentc

 Availableb

3678 (41.3)

5348 (51.0)

9026 (46.5)

<0.001

 Mean HIV RNA, log10 copies/ml (SD)

4.2 (1.0)

4.9 (0.9)

4.6 (1.0)

Hepatitis C co-infection

 Availableb

6913 (77.6)

6923 (66.0)

13836 (71.4)

<0.001

 No

3250 (45.2)

3942 (54.8)

7192 (52.0)

 Yes

3663 (55.1)

2981 (44.9)

6644 (48.0)

Hepatitis B co-infection

 Availableb

7832 (88.0)

7836 (74.7)

15668 (80.8)

<0.001

 No

6889 (50.8)

6669 (49.2)

13558 (86.5)

 Yes

943(44.7)

1167 (55.3)

2110 (13.5)

  1. aRow percentages bcolumn percentages. cViral load is available since 1996 and defined as viral load closest to and within 30 days since enrolment, including only treatment-naïve subjects at enrolment. CD4+ T cell count at enrolment is defined as CD4+ T cell count closest to and within 6 months since enrolment. IDUs Intravenous drug users, MSM Men who have sex with men
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