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Table 2 Model parameter assumptions used for estimation of Disability Adjusted Life Years

From: Randomized evaluation and cost-effectiveness of HIV and sexual and reproductive health service referral and linkage models in Zambia

Parameter

Assumption

Source

Discount rate

 

0.03

WHO recommendation

HIV incidence in Zambian pop.

Male

Female

UNAIDS Zambia 2014 [43]

 15–24

0.45 %

0.98 %

 25–29

0.01 %

0.05 %

 30–34

0.00 %

0.00 %

 35–39

0.00 %

0.01 %

 40+

0.00 %

0.01 %

HIV mortality (no ART)

 

0.0214

Lozano 2012 [44]

Incidence reduction from HTC

 Discordant couple

 

74.00 %

Allen 2014 [45]

 M-F couple

 

91.00 %

Allen 2014 [45]

Mortality reduction from ART

 

11.40 %

UNAIDS Zambia 2014 [43]

ART coverage

 

90.00 %

UNAIDS Zambia 2014 [43]

Prevalence reduction from VMMC

 

UNAIDS Zambia 2014 [43]

 15–24

 

1.10 %

 25–29

 

−7.00 %

 30–34

 

2.30 %

 35–39

 

13.70 %

 40+

 

22.90 %

Cervical cancer incidence

 

0.09

Sankaranarayanan 2006 [46]

Cervical cancer mortality

 

0.04

Sankaranarayanan 2006 [46]

Mortality reduction from CCS

 

81.00 %

Mandelblatt 2002 [47]