Klokwerk + study protocol: An observational study to the effects of night–shift work on body weight and infection susceptibility and the mechanisms underlying these health effects

Loef, Bette; van Baarle, Debbie; van der Beek, Allard J.; van Kerkhof, Linda W.; van de Langenberg, Daniëlla; Proper, Karin I.

doi:10.1186/s12889-016-3317-1

Table 2 Overview of the study parameters, measurement methods and instruments

From: Klokwerk + study protocol: An observational study to the effects of night–shift work on body weight and infection susceptibility and the mechanisms underlying these health effects

Parameter	Specification	Measurement method	Instrument	Source
Primary study parameters
(Night−) shift work^a	−Shift system	Questionnaire	Nightingale study questionnaire	Pijpe et al. 2014
	−Cumulative exposure
	−Shift intensity
Body weight^a	−Body height	Anthropometry	Direct body height, weight, and waist circumference measurements
	−Body weight
	−Waist circumference
	−BMI
Infection susceptibility	−Influenza like illness	Daily log (app)	Mobile phone application
Infection susceptibility	−Acute respiratory infection	Daily log (app)	Mobile phone application
Secondary study parameters
Sleep factors^a	−Sleep quantity	Questionnaire;	MOS Sleep Scale;	Hays et al. 2005
	−Sleep quality	Actigraphy	Actigraphy devices
	−Sleeping pattern	Actigraphy	Actigraphy devices
Physical activity^a	−Duration	Questionnaire;	SQUASH;	Wendel−Vos et al. 2003; Chau et al. 2011
	−Frequency	Actigraphy	WSQ;
	−Intensity		Actigraphy devices
	−Sedentary behavior		Actigraphy devices
Diet behaviors^a	−Timing of nutrition	Food diary	Food diary and FBCE	Lennernäs & Andersson 1999
	−Frequency of eating
	−Snacking behavior
Light exposure^a	−Artificial light exposure	Light sensor	HOBO Pendant Light Data Logger
Light exposure^a	−Sun light exposure	Light sensor	HOBO Pendant Light Data Logger
Vitamin D level^a	−Vitamin D level	Blood sample analyses	25−hydroxyvitamin D analysis
Immunological factors^a	−mRNA	Blood sample analyses	Transcriptomics; Thelper subset and cytokine profile analysis
	−Lymphocytes
	−Cytokine profiles
Other study parameters
Socio–demographic factors^a	−Age	Questionnaire	Dutch Public Health Monitor	GGD’en, CBS & RIVM, 2012
	−Gender
	−Ethnicity
	−Level of education
	−Employment status
	−Marital status
Smoking^a	−Smoking behavior	Questionnaire	Dutch Public Health Monitor	GGD’en, CBS & RIVM, 2012
Alcohol use^a	−Alcohol use behavior	Questionnaire	Dutch Public Health Monitor	GGD’en, CBS & RIVM, 2012
Job satisfaction	−Job satisfaction	Questionnaire	TAS	Smulders et al. 2001
Work−life balance	−Work–life balance	Questionnaire	SWING	Wagena & Geurts, 2000
Chronotype^a	−Morning/evening type	Questionnaire	MCTQ	Roenneberg et al. 2003
Sickness absenteeism	−Sickness absenteeism	Questionnaire	HPQ	Kessler et al. 2003
Sickness absenteeism	−Presenteeism	Questionnaire	HPQ	Kessler et al. 2003

BMI body mass index, CBS statistics Netherlands, FBCE food–based classification of eating episodes, GGD community health service, HPQ heath and work performance questionnaire, MCTQ Munich chrono type questionnaire, MOS Sleep Scale medical outcomes study sleep scale, RIVM national institute for public health and the environment, SQUASH short questionnaire to asses health enhancing physical activity, SWING survey work–home interference nijmeGen, TAS TNO work situation survey, WSQ workforce sitting questionnaire
^aStudy parameters that are also included in the Klokwerk study

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ISSN: 1471-2458

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