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Table 7 Power of given sample size between 6400 and 7400 participants recruited to detect expected hazard ratios

From: Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) – a Pan Canadian cohort study

Exposure Assumed prevalence of exposure Outcome Assumed incidence of Ooutcome Expected hazard ratio 7000/ (5920)1 6000 /(5120)1 5000/(4320)
Regional Wall Motion Abnormality 0.253 CVD 0.0598 2.60 >0.99/>0.99 >0.99/0.99 >0.99/>0.99
Silent Stroke 0.069 CVD 0.0598 2.85 >0.99 >0.99 >0.99
Liver Fata 0.063 T2DM 0.0974–0.1275 1.60 0.82 0.76 0.68
  1. 1 Assuming 20 % of the participants will have existing CVD the Number of Participants free of CVD and Cancer are shown in parenthesis; a (assuming a higher proportion of First Nations participants are retained, relative to other groups)