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Table 9 Exhaled breath biomarker summary and statistical comparisons

From: Reductions in biomarkers of exposure, impacts on smoking urge and assessment of product use and tolerability in adult smokers following partial or complete substitution of cigarettes with electronic cigarettes

  Exclusive e-Cigarette use groups Dual use groups Nicotine cessation
N = 13
Biomarker Tobacco rechargeable
N = 15
Cherry rechargeable
N = 13
Cherry disposable
N = 13
Tobacco rechargeable
N = 14
Cherry rechargeable
N = 15
Cherry disposable
N = 13
CO (ppm)       
 Day −1 27.2 ± 10.5 27.3 ± 6.9 26.9 ± 6.4 25.1 ± 7.3 25.4 ± 7.7 24.7 ± 5.5 29.3 ± 10.4
 Day 5 2.9 ± 0.8 2.9 ± 0.8 2.7 ± 0.9 17.3 ± 5.7 16.1 ± 3.3 18.2 ± 5.7 2.8 ± 0.7
 p-value Day −1 vs Day 5 <0.0001 <0.0001 <0.0001 0.0021 <0.0001 0.0002 <0.0001
 p-value Day 5 vs Cessation 0.7990 0.8033 0.9109 <0.0001 <0.0001 <0.0001 NA
NO (ppb)       
 Day −1 14.8 ± 12.8 11.5 ± 4.8 10.0 ± 4.0 14.9 ± 11.1 10.6 ± 4.6 14.3 ± 13.5 11.3 ± 4.0
 Day 5 23.3 ± 21.6 15.5 ± 9.0 14.3 ± 6.5 12.9 ± 6.3 10.7 ± 4.4 11.4 ± 6.0 16.8 ± 10.1
 p-value Day −1 vs Day 5 0.0075 0.1325 0.0053 0.3118 0.9415 0.3287 0.0321
 p-value Day 5 vs Cessation 0.2370 0.6031 0.5674 0.0313 0.0615 0.0119 NA
  1. Values are presented as mean ± SD