Table 2 Primary and secondary drug resistance pattern to first-line anti-TB drugs among culture positive pulmonary TB cases in Hitossa District, Arsi Zone of Oromia Region, Central Ethiopia 2015
Drug resistance pattern | New cases (N = 85) | Re-treated cases (N-21) | Total (N = 106) |
|---|---|---|---|
n (%) (95 % CI) | n (%) (95 % CI) | n (%) 95 % CI | |
Any R to one drug | 13 (15.2 % (7.6–22.8) | 11 (52.3: 30.9–73.7) | 24 (22.6: 14.6–30.6) |
Any INH | 8 (9.4 %) | 6 (28.6) | 14 (13.2) |
Any RIF | 4 (4.7) | 4 (19.0) | 8 (7.5) |
Any STM | 8 (9.4) | 5 (23.8) | 13 (12.3) |
Any EMB | 3 (3.5) | 2 (9.5) | 5 (4.7) |
Mono resistance | 4 | 4 | 8 |
Only INH | 2 (2.4) | 1 (4.8) | 3 (2.8) |
Only RIF | 0 | 0 | 0 |
Only STM | 2 (2.4) | 2 (9.5) | 4 (3.8) |
Only EMB | 0 | 1 (4.8) | 1 |
Two-drug resistance | 7 | 4 | 11 |
INH + RIF | 1 (1.2)* | 1 (4.8) | 2 (1.9)* |
INH + ETM | 1 (1.2) | 0 | 1 (0.9) |
INH + STM | 2 (2.4) | 2 (9.5) | 4 (3.8) |
RIF + EMB | 0 | 0 | 0 |
RIF + STM | 2 (2.4) | 1 (4.8) | 3 (2.8) |
ETM + STM | 1 (1.2) | 0 | 1 (0.9) |
Three or more-drug resistance | 2 | 3 | 5 |
INH + RIF + EMB | 0 | 0 | 0 |
INH + RIF + STM | 1 (1.2)* | 2 (9.5) | 3 (2.8)* |
INH + EMB + STM | 1 (1.2) | 0 | 1 (0.9) |
RIF + ETM + STM | 0 | 0 | 0 |
INH + RIF + EMB + STM | 0 | 1 (5.9) | 1 (0.9) |
MDR* | 2 (2.4) | 3 (14.3) | 5 (4.7) |