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Table 4 Odds of having individual metabolic syndrome components according to use of antidepressant medications in the Maine-Syracuse Longitudinal Study

From: Association between depressive symptoms, use of antidepressant medication and the metabolic syndrome: the Maine-Syracuse Study

Predictor Covariate seta Group MetS elevated glucoseb MetS hypertensionb MetS low HDL-cholesterolb
    OR 95 % CI P OR 95 % CI P OR 95 % CI P
Antidepressant medication use Basic Yes 2.01 1.30, 3.13 0.002 1.99 1.21, 3.25 0.006 1.66 1.10, 2.51 0.015
  No 1.00    1.00    1.00   
  Extended Yes 1.95 1.23, 3.09 0.005 1.81 1.09, 3.02 0.023 1.57 1.03, 2.40 0.036
   No 1.00    1.00    1.00   
  1. CI, confidence interval; MetS, metabolic syndrome; OR, odds ratio
  2. aBasic: adjusted for age, education, sex, ethnicity; Extended: adjusted for set 1 + smoking (cigarettes per day), physical activity (MET-minutes/day), CRP (mg/L)
  3. bMetS clinical cut off points: elevated fasting plasma glucose: ≥5.6 mmol/L or ≥100 mg/dL; elevated blood pressure: systolic: ≥130 and/or diastolic ≥85 mmHg; reduced HDL-cholesterol: <1.0 mmol/L or <40 mg/dL for males; <1.3 mmol/L or <50 mg/dL for females [1]