Association between depressive symptoms, use of antidepressant medication and the metabolic syndrome: the Maine-Syracuse Study

Table 3 Odds of having individual metabolic syndrome components according to depressed mood in the Maine-Syracuse Longitudinal Study

Depressive symptoms	Covariate set^a	Quartile of scores^b	MetS low HDL-cholesterol^c
Depressive symptoms	Covariate set^a	Quartile of scores^b	OR	95 % CI	P
CES-D score	Basic	Q4	1.89	1.30, 2.74	0.001
		Q3	1.28	0.89, 1.85	0.2
		Q2	1.41	0.98, 2.04	0.1
		Q1	1.00
	Extended	Q4	1.67	1.13, 2.46	0.010
		Q3	1.21	0.83, 1.77	0.3
		Q2	1.34	0.91, 1.98	0.1
		Q1	1.00
Zung score	Basic	Q4	1.48	1.02, 2.14	0.037
		Q3	1.36	0.93, 1.99	0.1
		Q2	1.01	0.71, 1.44	0.9
		Q1	1.00
	Extended	Q4	1.30	0.88, 1.91	0.2
		Q3	1.26	0.84, 1.87	0.3
		Q2	0.99	0.69, 1.44	0.9
		Q1	1.00

CES-D Center for Epidemiologic Studies Depression Scale; CI confidence interval; MetS metabolic syndrome; OR odds ratio
^aBasic: adjusted for age, education, sex, ethnicity; Extended: adjusted for set 1 + smoking (cigarettes per day), physical activity (MET-minutes/day), CRP (mg/L)
^bQuartile 1 (lowest quartile of scores) = reference group
^cMetS clinical cut off points: reduced HDL-cholesterol: <1.0 mmol/L or <40 mg/dL for males; <1.3 mmol/L or <50 mg/dL for females [1]

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