Skip to main content

Table 4 Association between parental smoking during pregnancy and risk of asthma at any time among offspring in married families

From: Parental smoking and cessation during pregnancy and the risk of childhood asthma

  No asthma N = 23427 Asthma N = 1741 Asthma prevalence (%) aOR*95%CI p-value**
No maternal smoking
Paternal non-smokera 14227 (60.7) 1040 (59.7) 6.8 1  
Paternal recent quitterb 1228 (5.2) 64 (3.7) 5.0 0.30 (0.2-0.4) <0.001
Paternal smoking 2967 (12.7) 251 (14.4) 7.8 3.01 (2.6-3.7) <.0.001
Maternal recent quitterb
Paternal non-smokera 679 (2.9) 51 (2.9) 7.8 1.12 (0.8-1.5) 0.0483
Paternal recent quitterb 528 (2.3) 35 (2.0) 6.2 0.50 (0.3-0.7) <0.001
Paternal smoking 1008 (4.3) 87 (5.0) 7.9 2.71 (2.1-3.5) <.0.001
Maternal smoking
Paternal non-smokera 323 (1.4) 27 (1.6) 7.7 1.59 (1.0-2.5) 0.042
Paternal recent quitterb 280 (1.2) 13 (0.7) 4.4 0.22 (0.1-0.4) <0.001
Paternal smoking 966 (4.1) 101 (5.8) 9.5 3.94 (3.1-5.1) <0.001
Missing data 1221 (5.2) 72 (4.1) 5.6   
  1. aNo smoking before or during pregnancy
  2. bQuit smoking prior to or during pregnancy
  3. *Adjusted for the following maternal factors at birth: asthma, age, parity, pre-pregnancy BMI and ART, plus gender of child, gestational weeks at birth, mode of delivery and age of asthma or among controls follow-up time
  4. **p-value for adjusted analysis obtained from the trend test (Wald) in logistic regression model