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Table 3 Disease transition probabilities showing annual progression risk. The possibility of transition from one HIV health state to the next is described. The estimates were obtained from relevant South African literature for the year 2012

From: Projected economic evaluation of the national implementation of a hypothetical HIV vaccination program among adolescents in South Africa, 2012

Parameter

Distribution

Estimate

Reference

Change in HIV disease state

   

 Asymptomatic to symptomatic

Beta

0.32

[54]

 Symptomatic to AIDS

Beta

0.20

[55]

 AIDS to death

Beta

0.21

[54]

Change in drug regimens

   

 First-line to second-line

Beta

0.10

[55]

 Second-line to third-line

Beta

0.01

[56]