Biochemical profiles | Asian Reference range | Orang Asli (female) | CV | ||||||
---|---|---|---|---|---|---|---|---|---|
Inland | Periphery | ||||||||
Semai (n = 24) | Bateq (n = 4) | Lanoh (n = 11) | Kanaq (n = 9) | Kensiu (n = 39) | Che Wong (n = 19) | Malay (n = 89) | |||
Lipid profile | |||||||||
TC, mmol/La | Mean (SD) | 4.35 (0.92) | 4.35 (0.71) | 4.90 (1.22) | 4.91 (0.69) | 4.60 (0.98) | 5.28 (1.37)c | 5.20 (0.85)c,h | 0.81 |
% of the subjects | >5.2 | 25.00 | 0 | 45.45 | 33.33 | 25.64 | 47.37 | 49.44 | |
HDL-C, mmol/Lb | Mean (SD) | 1.10 (0.40) | 1.45 (0.10)c | 1.20 (0.60) | 0.90 (0.30)c,d | 0.90 (0.20)c,d | 1.20 (0.60)g,h | 1.70 (0.50)c,e,g,h,i | 1.13 |
% of the subjects | <1.0 | 16.67 | 0 | 36.36 | 66.67 | 51.28 | 31.58 | 1.12 | |
LDL-C, mmol/La | Mean (SD) | 2.77 (0.74) | 2.58 (0.53) | 3.16 (1.01) | 3.38 (0.62) | 3.09 (0.93) | 3.55 (1.05) | 3.15 (0.78) | 1.10 |
% of the subjects | >4.1 (very high risk) | 4.17 | 0 | 18.18 | 33.33 | 10.26 | 21.05 | 14.77 | |
<4.1 (high risk) | 16.67 | 0 | 27.27 | 11.11 | 33.33 | 31.58 | 20.45 | ||
<3.4 (moderate) | 45.83 | 50.00 | 36.36 | 55.56 | 17.95 | 31.58 | 43.18 | ||
<2.6 (low risk) | 33.33 | 50.00 | 18.18 | 0 | 38.46 | 15.79 | 21.59 | ||
TG, mmol/Lb | Mean (SD) | 0.85 (0.80) | 0.60 (0.50) | 1.00 (0.80) | 1.40 (0.50)c,d | 0.90 (0.70)g | 0.80 (0.50)g | 0.70 (0.40)g,h | 1.60 |
% of the subjects | >1.7 | 16.67 | 0 | 18.18 | 11.11 | 10.26 | 15.79 | 3.37 | |
Endocrine tests | |||||||||
FBG, mmol/Lb | Mean (SD) | 4.80 (0.70) | 5.95 (0.40) | 5.40 (1.10)c,d | 4.90 (0.50)c,i | 4.90 (1.20/ | 4.90 (1.30)c,h | 4.90 (0.50)c,h,i | 0.38 |
% of the subjects | 3.5–6.0 (normal) | 91.67 | 50.00 | 72.72 | 62.50 | 83.33 | 94.74 | 100.00 | |
6.1–6.9 (IFG) | 8.33 | 50.00 | 27.27 | 25.00 | 5.56 | 5.26 | 0 | ||
>7.0 (DM) | 0 | 0 | 0 | 12.50 | 11.11 | 0 | 0 | ||
HbAlc, %a | Mean (SD) | 5.05 (0.31) | 5.03 (0.47) | 5.33 (0.29) | - | 5.43 (0.30)c | 5.16 (0.21)h | 5.35 (0.24)c | 0.80 |
% of the subjects | <4.8 | 17.39 | 33.33 | 0 | - | 0 | 0 | 0 | |
4.8–5.9 | 82.61 | 66.67 | 90.91 | - | 94.44 | 100.00 | 98.86 | ||
>5.9 | 0 | 0 | 9.09 | - | 5.55 | 0 | 1.14 | ||
Insulin, pmol/Lb | Mean (SD) | 52.40 (85.00) | 62.30 (82.30) | 133.80 (157.80)c,d | 19.90 (33.80)c,i | 47.2 (76.00)g,i | 169.30 (368.30)c,g,h | 47.10 (34.50)e,g,i | 1.70 |
% of the subjects | <17.8 | 0 | 25.00 | 0 | 22.22 | 20.51 | 0 | 3.37 | |
17.8–173.0 | 91.67 | 75.00 | 63.64 | 66.67 | 10.53 | 52.63 | 94.38 | ||
>173.0 | 8.33 | 0 | 36.36 | 0 | 72.22 | 47.37 | 0 | ||
hs-CRP, nmol/Lb | Mean (SD) | 8.70 (19.30) | 27.60 (44.30) | 32.40 (42.90) | 16.2 (98.10) | 5.00 (19.30)c | 9.40 (37.20) | 5.70 (10.00)c,i | 0.60 |
% of the subjects | <9.5 (low risk) | 54.17 | 50.00 | 36.36 | 33.33 | 17.95 | 52.63 | 15.73 | |
9.5–28.6 (moderate) | 33.33 | 0 | 9.09 | 22.22 | 64.10 | 15.79 | 70.79 | ||
>28.6 (high risk) | 12.50 | 50.00 | 54.55 | 44.44 | 17.95 | 31.58 | 13.48 | ||
Renal profile | |||||||||
Urea, mmol/La | <8.3 | 3.25 (0.88) | 3.93 (0.74) | 3.47 (1.72) | 3.09 (105) | 2.82 (0.96) | 3.32 (0.67) | 3.25 (0.80) | 2.30 |
Creatinine, | <80 | 58.92 | 66.00 | 62.91 | 83.78(12.4 | 58.87(11.4 | 71.68(14.94 | 57.42(7.20)e,g | 3.10 |
micromol/La | (8.97) | (19.51) | (21.48) | 3)c | 1)g | ) | |||
Sodium, mmol/Lb | 136.0–145.0 | 139.95 (2.60) | 140.00(8.80) | 138.00 (3.00)c | 138.00 (2.50)c | 142.00 (8.60)i | 140.70 (3.50)g,i | 137.00 (2.00)c,e,g,h | 0.24 |
Potassium nmol/La | 3.5–5.1 | 4.00 (0.25) | 3.53 (0.57) | 3.53 (0.21)c | 4.10 (0.17)i | 3.78 (0.47)g | 4.13 (0.35)h,i | 4.69 (0.45)c,e,g,h,i | 0.44 |
Liver function tests | |||||||||
Albumin, g/Lb | 35.0–52.0 | 44.45 (2.90) | 45.90 (3.20)c | 46.20 (4.70)c | 46.20 (2.90) | 44.50 (3.00)d,g,i | 48.90 (3.60)c,g,h | 49.20 (3.70)g,h,i | 1.90 |
Total protein, g/Lb | 66.0–87.0 | 73.45 (5.40) | 77.45 (56.90) | 81.70 (4.20)c,d | 77.80 (3.80)c,i | 75.20 (5.30)i | 79.10 (6.50)c,h | 77.40 (6.70)c,h,i | 1.12 |
ALP, U/La | 35.0–104.0 | 79.76 (19.00) | 92.55 (26.00) | 89.80 (22.14) | 76.86 (16.55) | 80.06 (27.82) | 73.73 (26.31) | 60.18 (16.41)c’dhi | 1.60 |
ALT, U/La | <33.0 | 16.60 (7.17) | 14.98 (14.82) | 13.59 (21.12)c | 9.17 (6.61) | 14.25 (9.38) | 27.31 (28.83)g,i | 11.80 (7.74)c,e | 1.00 |
Direct bilirubin, pmol/Lb | <5.1 | 2.00 (110) | 2.20 (2.20) | 2.80 (2.20)c | - | 0.80 (1.00)c,d,i | 0.90 (0.40)c,d,i | 2.40 (1.20)c,e,h | 6.40 |
Total bilirubin, pmol/La | <21.0 | 8.49 (3.30) | 6.90 (2.95) | 9.51 (5.52) | - | 3.39 (2.15)c,i | 4.43 (1.46)c,h,i | 7.04 (2.91)c,h,i | 0.46 |
GGT, U/Lb | <40.0 | 14.45 (13.90) | 23.70 (52.80) | 15.80 (25.10) | 8.20 (8..80)c | 20.90 (25.70)g | 17.40 (20.60)g | 10.30 (6.10)c,d,e,h | 1.80 |
Ferritin, pmol/Lb | 29.2–337.1 | 167.20 (149.50) | 35.05 (84.60) | 86.70 (152.60)c,d | 50.80 (145.10)c,i | 54.40 (114.70)g,i | 40.90 (46.10)c,g,h | 96.00 (118.60)e,g,i | 1.80 |