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Table 3 Risk of low birth weight associated with maternal urinary manganese levels, stratified by maternal age

From: Maternal urinary manganese and risk of low birth weight: a case–control study

Manganese levelsa Age < 28 years old (n = 392) Age ≥ 28 years old (n = 424) P for heterogeneity
Ca/Co ORb (95 % CI) ORc (95 % CI) Ca/Co ORb (95 % CI) ORc (95 % CI)
Tertile 1 31/98 1.80 (0.91, 3.56) 1.88 (0.74, 4.80) 23/106 0.72 (0.39, 1.34) 0.84 (0.31, 2.24) 0.19
Tertile 2 17/98 1.00 1.00 31/106 1.00 1.00  
Tertile 3 50/98 3.14 (1.67, 5.92) 2.74 (1.07, 7.03) 52/106 1.69 (0.98, 2.90) 1.98 (0.82, 4.74)  
  1. Abbreviations: ca/co, numbers of cases and controls; CI confidence interval; OR odds ratio
  2. a Manganese levels (μg/g creatinine): age < 28 years, tertile 1 (<0.30), tertile 2 (0.30–1.08), tertile 3 (≥1.09); age ≥ 28 years, tertile 1 (<0.28), tertile 2 (0.28–1.21), tertile 3(≥1.22)
  3. b Crude odds ratio
  4. c Adjusted for gestational age, household income, pre-pregnancy body mass index, parity, passive smoking, and gestational hypertension