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Table 4 Cord blood analyses

From: Maternal, fetal and perinatal alterations associated with obesity, overweight and gestational diabetes: an observational cohort study (PREOBE)

 

N

Normal weight n ≤ 76

Overweight or obese n ≤ 62

Gestational diabetes n ≤ 45

P

Iron status

 Ferritin (μg/l)

119

168 (103–265)

163 (115–233)

139 (88–268)

0.930

 TS (%)

49

60.7 ± 2.1

55.1 ± 17.7

64.3 ± 20.0

0.254

 Hb (g/l)

125

16.7 ± 1.6

17.0 ± 2.4

16.3 ± 2.1

0.359

 MCV (fl)

125

107.5 ± 5.4

107.0 ± 6.5

107.9 ± 3.7

0.776

Vitamins

 Vitamin B12 (pg/ml)

45

665 ± 512

436 ± 198

739 ± 333

0.005

 Folate (ng/ml)b

150

>20 (16.6– > 20)

19.9 (15.5– > 20)

>20 (>20– > 20)a

0.010

Other biomarkers

 Glucose (g/l)

156

69.7 ± 21.1

66.2 ± 22.2

77.4 ± 22.4

0.050

 Insulin (μU/ml)

118

3.5 (2.2–5.8)

4.4 (2.9–7.3)

5.6 (2.0–10.3)

0.126

 HbA1c (%)

34

3.2 (3.0–3.5)

3.3 (3.2–3.5)

3.7 (3.3–4.4)

0.064

 Uric acid (mg/dl)

132

4.92 ± 0.90

4.95 ± 1.29

4.94 ± 1.06

0.995

 Creatinine (mg/dl)

131

0.60 ± 0.18

0.63 ± 0.23

0.61 ± 0.21

0.712

 TSH (ng/ml)

133

11.0 (7.3–15.3)

8.4 (6.3–14.4)

8.1 (5.5–12.2)

0.270

 CRP (mg/dl)

47

0.00 (0.00–0.10)

0.01 (0.00–0.03)

0.01 (0.07–0.10)

0.308

 Cortisol (μg/dl)

47

13.6 ± 4.5

13.7 ± 10.3

11.6 ± 5.7

0.678

  1. Data are mean ± SD, n (%), or median (IQR) and p-values are ANOVA, Chi square test, or Kruskal Wallis rank sum test respectively
  2. aSignificantly different from normal group in a multiple-comparison-adjusted-post hoc test
  3. bHighest detectable folate level was 20 ng/ml