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Table 3 Comparison of consumption in DDD-10,000 inhabitants in the three Brazilian cities studied

From: Essential psychiatric medicines: wrong selection, high consumption and social problems

ATC code

Generic names

Presence in WHO/RENAME and/or RESME

City 1

City 2

City 3

Mean + Std Dev(%)

2009

2010

2010

 

Antidepressants Total

-

242.6

229.9

253.7

242.1 ± 11.9 (100 %)

N06AA

Tricyclic Antidepressants

-

40.3

37.4

35.6

37.7 ± 2.3 (15.5)

N06AA09

amitriptyline

Y

21.0

25.9

26.5

24.4 ± 3.0 (10.1)

N06AA04

clomipramine

Y

5.2

5.9

3.8

4.9 ± 1.1 (2.0)

N06AA10

nortriptyline

Y

0.6

2.3

1.6

1.5 ± 0.8 (0.6)

N06AA02

imipramine

N

13.5

3.1

3.6

6.7 ± 5.8 (2.7)

N06AB

SSRI Antidepressants a

-

202.3

192.5

218.1

204.3 ± 12.9 (84.3)

N06AB03

fluoxetine

Y

152.9

136.1

161.1

150.0 ± 12.7 (61.9)

N06AB06

sertraline

N

49.3

56.4

56.9

54.2 ± 4.2 (22.4)

N06AB04

citalopram

N

0.1

NA

NA

-

N06AX

Other Antidepressants

 

1.9

-

-

-

N06AX12

bupropion

Y

1.9

NA

NA

-

N03AE/ N05BA/N05CD

Benzodiazepines Total

-

161.9

117.1

98.1

125.7 ± 32.7 (100 %)

N05CD08

midazolam

Y

NA

0.004

NA

-

N05CD02

nitrazepam

N

31.3

11.3

11.7

18.1 ± 11.4 (14.4)

N03AE01

clonazepam

Y

11.1

19.5

28.8

19.8 ± 8.8 (15.7)

N05BA09

clobazam

N

1.4

NA

NA

-

N05BA01

diazepam

Y

118.1

86.3

57.6

87.3 ± 30.2 (69.4)

  1. Y yes, the medicine is present on the list, N no, the medicine is not present on the list, NA not available
  2. aSSRI antidepressants selective serotonin reuptake inhibitor antidepressants