Table 3 PPV of the test, participation, lesion and colonoscopy rates following positive test result, by age group
Women | Men | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Age groups | successfully-invited population | no. of participants | % participation | OR | (95 % CI) | Age groups | successfully-invited population | no. of participants | % participation | OR | (95 % CI) |
50-54 | 37379 | 24609 | 65.84 | 1.00 | 50-54 | 36221 | 21033 | 58.07 | 1.00 | ||
55-59 | 27637 | 19375 | 70.11 | 1.22 | (1.18-1.26) | 55-59 | 26324 | 16692 | 63.41 | 1.25 | (1.21-1.29) |
60-64 | 28760 | 20434 | 71.05 | 1.27 | (1.23-1.32) | 60-64 | 26866 | 18144 | 67.54 | 1.50 | (1.45-1.55) |
64-69 | 18758 | 12635 | 67.36 | 1.07 | (1.03-1.11) | 64-69 | 17175 | 11457 | 66.71 | 1.45 | (1.40-1.51) |
p < 0.001 | p < 0.001 | ||||||||||
Age groups | no. of participants | no. of lesions (premal. + malignant) | rate of lesions (premal. + malignant) among participantsa | OR | (95 % CI) | Age groups | no. of participants | no. of lesions (premal. + malignant) | rate of lesions (premal. + malignant) among participants | OR | (95 % CI) |
50-54 | 24609 | 302 | 12.27 | 1.00 | 50-54 | 21033 | 593 | 28.19 | 1.00 | ||
55-59 | 19375 | 273 | 14.09 | 1.15 | (0.97-1.35) | 55-59 | 16692 | 777 | 46.55 | 1.7 | (1.51-1.88) |
60-64 | 20434 | 357 | 17.47 | 1.43 | (1.22-1.66) | 60-64 | 18144 | 1058 | 58.31 | 2.1 | (1.93-2.37) |
64-69 | 12635 | 257 | 20.34 | 1.66 | (1.41-1.97) | 64-69 | 11457 | 799 | 69.74 | 2.6 | (2.31-2.87) |
p < 0.001 | p < 0.001 | ||||||||||
Age groups | no. of participants | no. of malignant lesions | rate of malignant lesions among participantsa | OR | (95 % CI) | Age groups | no. of participants | no. of malignant lesions | rate of malignant lesions among participants | OR | (95 % CI) |
50-54 | 24609 | 38 | 1.54 | 1.00 | 50-54 | 21033 | 47 | 2.23 | 1.00 | ||
55-59 | 19375 | 37 | 1.91 | 1.24 | (0.78-1.95) | 55-59 | 16692 | 77 | 4.61 | 2.07 | (1.45-3.00) |
60-64 | 20434 | 59 | 2.89 | 1.87 | (1.25-2.83) | 60-64 | 18144 | 119 | 6.56 | 2.97 | (2.13-4.20) |
64-69 | 12635 | 47 | 3.72 | 2.40 | (1.56-3.70) | 64-69 | 11457 | 126 | 11.00 | 5.02 | (3.62-7.10) |
p < 0.001 | p < 0.001 | ||||||||||
Age groups | no. of participants | no. of carcinomas stage III/IV | no. of carcinomas stage III/IV | OR | (95 % CI) | Age groups | no. of participants | no. of carcinomas stage III/IV | no. of carcinomas stage III/IV | OR | (95 % CI) |
50-54 | 24609 | 16 | 0.65 | 1.00 | 50-54 | 21033 | 10 | 0.48 | 1.00 | ||
55-59 | 19375 | 15 | 0.77 | 1.19 | (0.58-2.41) | 55-59 | 16692 | 19 | 1.14 | 2.40 | (1.14-5.37) |
60-64 | 20434 | 22 | 1.08 | 1.65 | (0.87-3.19) | 60-64 | 18144 | 37 | 2.04 | 4.33 | (2.24-9.20) |
64-69 | 12635 | 10 | 0.79 | 1.20 | (0.52-2.61) | 64-69 | 11457 | 44 | 3.84 | 8.23 | (4.32-17.34) |
p = 0.488 | p < 0.001 | ||||||||||
Age groups | people with + FOBT | people who had colonoscopy | % colonoscopies | OR | (95 % CI) | Age groups | people with + FOBT | people who had colonoscopy | % colonoscopies | OR | (95 % CI) |
50-54 | 955 | 881 | 92.25 | 1.00 | 50-54 | 1360 | 1259 | 92.57 | 1.00 | ||
55-59 | 827 | 773 | 93.47 | 1.17 | (0.82-1.69) | 55-59 | 1458 | 1363 | 93.48 | 1.17 | (0.87-1.57) |
60-64 | 1083 | 991 | 91.51 | 0.90 | (0.65-1.23) | 60-64 | 1871 | 1739 | 92.94 | 1.06 | (0.81-1.39) |
64-69 | 785 | 720 | 91.72 | 0.91 | (0.64-1.29) | 64-69 | 1339 | 1266 | 94.55 | 1.40 | (1.03-1.92) |
p = 0.446 | p = 0.150 | ||||||||||
Age groups | people who had colonoscopy | no. of lesions (premal. + malignant) | % lesions found in colonoscopy | OR | (95 % CI) | Age groups | people who had colonoscopy | no. of lesions (premal. + malignant) | % lesions found in colonoscopy | OR | (95 % CI) |
50-54 | 881 | 302 | 34.28 | 1.00 | 50-54 | 1259 | 593 | 47.10 | 1.00 | ||
55-59 | 773 | 273 | 35.32 | 1.05 | (0.85-1.28) | 55-59 | 1363 | 777 | 57.01 | 1.49 | (1.27-1.73) |
60-64 | 991 | 357 | 36.02 | 1.08 | (0.89-1.30) | 60-64 | 1739 | 1058 | 60.84 | 1.75 | (1.51-2.02) |
64-69 | 720 | 257 | 35.69 | 1.07 | (0.87-1.31) | 64-69 | 1266 | 799 | 63.11 | 1.92 | (1.64-2.25) |
p = 0.883 | p < 0.001 | ||||||||||
Age groups | people with + FOBT | no. of lesions (premal. + malignant) | PPV | OR | (95 % CI) | Age groups | people with + FOBT | no. of lesions (premal. + malignant) | PPV | OR | (95 % CI) |
50-54 | 955 | 302 | 31.62 | 1.00 | 50-54 | 1360 | 593 | 43.60 | 1.00 | ||
55-59 | 827 | 273 | 33.01 | 1.06 | (0.87-1.30) | 55-59 | 1458 | 777 | 53.29 | 1.48 | (1.27-1.71) |
60-64 | 1083 | 357 | 32.96 | 1.06 | (0.88-1.28) | 60-64 | 1871 | 1058 | 56.55 | 1.69 | (1.46-1.94) |
64-69 | 785 | 257 | 32.74 | 1.06 | (0.86-1.29) | 64-69 | 1339 | 799 | 59.67 | 1.91 | (1.64-2.23) |
p = 0.919 | p < 0.001 | ||||||||||