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Table 2 Adjusted HR (95 % CI) for allergy medication, in relation to traffic-related exposure, n = 7898

From: Ever dispense of prescribed allergy medication in children growing up close to traffic: a registry-based birth cohort

Allergy medicationa   
  Nasal anti-allergics Oral antihistamine
1st purchase 1st purchase
Heaviest road ≤100 m, birth addressb
 0–8639 cars/day 1.0 1.0
  ≥ 8640 0.89 (0.61–1.29) 0.91 (0.83–1.00)
Heaviest road ≤100 m, never movedb
 0–8639 cars/day 1.0 1.0
  ≥ 8640 0.83 (0.51–1.36) 0.90 (0.79–1.03)
NOX, birth addressc
  ≤ 15 μg/m3 1.0 1.0
 15–25 0.84 (0.58–1.21) 0.86 (0.77–0.95)
  > 25 0.86 (0.50–1.49) 0.81 (0.68–0.96)
NOX, never movedc
  ≤ 15 μg/m3 1.0 1.0
 15–25 0.95 (0.62–1.47) 0.88 (0.78–0.99)
  > 25 0.95 (0.42–2.16) 0.77 (0.62–0.96)
NOX, lifetime meand
  ≤ 15 μg/m3 1.0 1.0
 15–25 0.92 (0.62–1.35) 0.84 (0.75–0.93)
  > 25 0.59 (0.23–1.50) 0.70 (0.56–0.89)
  1. aAdjusted for sex, season, parental origin, year of birth, breastfeeding, and parental allergy
  2. bn = 6093 children had complete covariate information and traffic exposure assessments
  3. cn = 6091 children had complete covariate information and modeled NOx concentrations
  4. dThe number of children with complete covariate information and modeled mean NOx during time at risk, was n = 5264 for nasal antiallergics, and n = 5317 for oral antihistamines
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